Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 2/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8684139 | 0.85 | RAD51 (0.39) | SCN2AF2RL3 | |
| SCHEMBL2265845 | 0.81 | PARP1 (0.42) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL4047695 | 0.75 | IDO1 (0.46) | IDO1KDM4EALDH1A1LMNASCN2A | |
| SCHEMBL8684313 | 0.74 | CA12 (0.41) | KDM4EALDH1A1LMNA | |
| SCHEMBL1348539 | 0.73 | KDM4E (0.49) | IDO1KDM4EALDH1A1LMNACYP1A2 | |
| SCHEMBL8684094 | 0.71 | SMN1; SMN2 (0.42) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL13733242 | 0.71 | ALDH1A1 (0.52) | IDO1KDM4EALDH1A1LMNACYP1A2 | |
| SCHEMBL9383785 | 0.71 | KDM4E (0.56) | IDO1KDM4EALDH1A1LMNACYP1A2 | |
| SCHEMBL10850137 | 0.70 | KDR (0.59) | KDM4EALDH1A1LMNACYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL8685739 | 0.70 | TLR8 (0.47) | IDO1KDM4EALDH1A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723481-A | ANTIULCER AGENTS AND 5-LIPOXYGENASE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 1998-03-03 | — | — | US | disclosed |
| US-5698576-A | POSSESS ANTI-ULCER AND 5-LIPOXYGENASE INHIBITORY ACTIVITIES | SANKYO COMPANY, LIMITED (JP) | 1997-12-16 | — | — | US | disclosed |
| US-5665752-A | LIPOXYGENASE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 1997-09-09 | — | — | US | disclosed |
| US-5354768-A | Use of imidazopyrazole derivatives as analgesics and anti-inflammatory agents | SANKYO COMPANY, LIMITED (JP) | 1994-10-11 | — | — | US | disclosed |
| EP-0353047-B1 | Use of imidazopyrazole derivatives as analgesics and anti-inflammatory agents | SANKYO CO (JP) | 1994-10-05 | — | — | EP | disclosed |
| US-5308542-A | Stability, heat and electrical resistance; dielectic anisotropy | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-05-03 | — | — | US | disclosed |
| US-5232939-A | Use of imidazopyrazole derivatives as analgesics and anti-inflammatory agents | SANKYO COMPANY LIMITED (JP) | 1993-08-03 | — | — | US | disclosed |