SCHEMBL1126957

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1126880	0.86	CNR2 (0.48)	ALDH1A1TSHRPOLBKDM4EHTT
	SCHEMBL1126803	0.86	ALDH1A1 (0.54)	ALDH1A1TSHRPOLBL3MBTL1KDM4E
	SCHEMBL1126875	0.82	MEN1 (0.51)	ALDH1A1TSHRMAPTMEN1KMT2A
	SCHEMBL1126839	0.82	ALDH1A1 (0.46)	ALDH1A1TSHRPOLBL3MBTL1KDM4E
	SCHEMBL1126744	0.78	ALDH1A1 (0.45)	ALDH1A1TSHRKDM4EHTTMAPT
	SCHEMBL1126585	0.77	BRD4 (0.42)	ALDH1A1TSHRL3MBTL1KDM4EMAPT
	SCHEMBL1126926	0.77	SLC18A3 (0.43)	ALDH1A1TSHRKDM4ESMN1; SMN2CYP1A2
	SCHEMBL1127276	0.76	BRD4 (0.40)	ALDH1A1TSHRKDM4ESMN1; SMN2GAA
	SCHEMBL1126874	0.76	CA12 (0.52)	ALDH1A1TSHRPOLBL3MBTL1KDM4E
	SCHEMBL14947704	0.75	NTSR1 (0.57)	ALDH1A1TSHRPOLBL3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.