Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.57 |
| ▸ | CES2 | O00748 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2376839 | 0.80 | MAPT (0.58) | CES1CES2RAB9ALMNAMAPT | |
| SCHEMBL12985768 | 0.78 | CES1 (0.59) | CES1CES2RAB9ALMNAMAPT | |
| SCHEMBL7669290 | 0.73 | CES2 (1.00) | CES1CES2RAB9ALMNAMAPT | |
| SCHEMBL4625390 | 0.73 | CES2 (1.00) | CES1CES2RAB9ALMNAMAPT | |
| SCHEMBL6206988 | 0.72 | CES1 (0.55) | CES1CES2RAB9ALMNAMAPT | |
| SCHEMBL9818176 | 0.69 | CES1 (0.52) | CES1CES2RAB9ALMNAMAPT | |
| SCHEMBL9710316 | 0.69 | CES1 (0.63) | CES1CES2RAB9ALMNAMAPT | |
| SCHEMBL31175926 | 0.69 | CES2 (0.76) | CES1CES2RAB9ALMNAMAPT | |
| SCHEMBL27908851 | 0.69 | CES1 (0.52) | CES1CES2RAB9ALMNAMAPT | |
| SCHEMBL5698372 | 0.69 | CES1 (0.52) | CES1CES2RAB9ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750560-A | ANTICOAGULANTS; FREE RADICAL SCAVENGERS; CARDIOVASCULAR, GASTROINTESTINAL, NERVOUS SYSTEM AND RESPIRATORY SYSTEM DISORDERS | LABORATOIRES DE THERAPEUTIQUE MODERNE (FR) | 1998-05-12 | — | — | US | disclosed |
| US-5470871-A | Free radical scavengers, microbiocides and calcium or potassium channel activators for cardiovascular disorders, nervous system disorders or respiratory system disorders | LABORATOIRES DE THERAPEUTIQUE MODERNE (FR) | 1995-11-28 | — | — | US | disclosed |