Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 7/20 | 0.52 |
| ▸ | CES2 | O00748 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27908851 | 1.00 | CES1 (0.52) | CES1CES2ALDH1A1MAPK1TRPA1 | |
| SCHEMBL31264363 | 0.83 | CES1 (0.55) | CES1CES2MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL9818176 | 0.83 | CES1 (0.52) | CES1CES2ALDH1A1MAPK1MAPT | |
| SCHEMBL8158420 | 0.81 | CES1 (0.50) | CES1CES2ALDH1A1MAPK1MAPT | |
| SCHEMBL9818141 | 0.81 | CES1 (0.50) | CES1CES2ALDH1A1MAPK1MAPT | |
| SCHEMBL1982008 | 0.81 | CES2 (0.50) | CES1CES2MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL1982010 | 0.81 | CES2 (0.50) | CES1CES2MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL20564211 | 0.81 | CES1 (0.50) | CES1CES2ALDH1A1MAPK1MAPT | |
| SCHEMBL20564213 | 0.81 | CES1 (0.50) | CES1CES2ALDH1A1MAPK1MAPT | |
| SCHEMBL8408970 | 0.81 | CES1 (0.50) | CES1CES2ALDH1A1MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144542-B1 | POLYMER CEMENT ADDITIVE, CEMENT COMPOSITION AND PROCESS THEREWITH | CONOCOPHILLIPS CO (US) | 2006-07-19 | — | — | EP | claimed |