SCHEMBL8685366

SCHEMBL8685366

O=C1c2ccc3c4ccc5c6c(ccc(c7ccc(c2c37)C(=O)N1Cc1cccc(Cl)c1)c64)C(=O)N(Cc1cccc(Cl)c1)C5=O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 0.60
▸ KDM4E B2RXH2 2/20 0.60
▸ MAPK1 P28482 1/20 0.60
▸ KMT2A Q03164 6/20 0.59
▸ MEN1 O00255 3/20 0.59
▸ HPGD P15428 1/20 0.59
▸ NPSR1 Q6W5P4 1/20 0.55
▸ CASP6 P55212 1/20 0.54
▸ LMNA P02545 2/20 0.51
▸ CYP1B1 Q16678 2/20 0.51
▸ RGS12 O14924 1/20 0.51
▸ USP2 O75604 1/20 0.51
▸ HTT P42858 1/20 0.51
▸ RECQL P46063 1/20 0.51
▸ ATM Q13315 1/20 0.50
▸ TYR P14679 1/20 0.50
▸ CACNA1G O43497 2/20 0.46
▸ UBE2N P61088 1/20 0.46
▸ TDP1 Q9NUW8 1/20 0.46
▸ CA12 O43570 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14302829 0.86 ALDH1A1 (0.54) MAPTKDM4EMAPK1KMT2AMEN1
SCHEMBL8680716 0.84 NPSR1 (0.65) MAPTKMT2AMEN1HPGDNPSR1
SCHEMBL18669170 0.83 KDM4E (0.73) MAPTKDM4EMAPK1KMT2AMEN1
SCHEMBL14303158 0.83 CA12 (0.55) MAPTKDM4EKMT2AMEN1NPSR1
SCHEMBL14303138 0.82 UBE2N (0.63) MAPTKMT2AMEN1HPGDNPSR1
SCHEMBL8153395 0.82 NPSR1 (0.72) MAPTKDM4EKMT2AMEN1HPGD
SCHEMBL14302318 0.82 TERT (0.50) MAPTKMT2AMEN1HPGDNPSR1
SCHEMBL24813824 0.79 KMT2A (0.72) MAPTKMT2AMEN1HPGDNPSR1
SCHEMBL8680697 0.79 KDM4E (0.63) MAPTKDM4EMAPK1KMT2AMEN1
SCHEMBL17514372 0.78 NPSR1 (0.54) MAPTKMT2AMEN1HPGDNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090104551-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING METHOD AND IMAGE FORMING KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2009-04-23 — — US disclosed
US-20090104551-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING METHOD AND IMAGE FORMING KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2009-04-23 — — US disclosed
US-20090040609-A1 COMPOSITION FOR ANISOTROPIC DYE FILM, ANISOTROPIC DYE FILM, AND POLARIZING DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2009-02-12 — — US disclosed
US-20090040609-A1 COMPOSITION FOR ANISOTROPIC DYE FILM, ANISOTROPIC DYE FILM, AND POLARIZING DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2009-02-12 — — US disclosed
US-7459256-B2 Image forming method and image forming apparatus KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2008-12-02 — — US disclosed
US-7459256-B2 Image forming method and image forming apparatus KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2008-12-02 — — US disclosed
EP-0977754-B1 WRITABLE AND ERASABLE HIGH-DENSITY OPTICAL STORAGE MEDIA CIBA SC HOLDING AG (CH) 2008-01-16 — — EP disclosed
US-5853933-A Photoconductive member and perylene processes XEROX CORPORATION (US) 1998-12-29 — — US disclosed
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