Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8685466 | 1.00 | KDM1A (0.41) | KDM1AKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6959889 | 0.77 | NPC1 (0.49) | KDM1AKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6959884 | 0.77 | NPC1 (0.49) | KDM1AKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8687832 | 0.73 | KDM4E (0.41) | KDM1AKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8687836 | 0.73 | KDM4E (0.41) | KDM1AKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8685471 | 0.72 | KMT2A (0.43) | KMT2AMEN1ALDH1A1SMN1; SMN2CDC7 | |
| SCHEMBL25154819 | 0.69 | EPHX2 (0.42) | KDM1AKMT2ACFD | |
| SCHEMBL6957562 | 0.69 | ALDH1A1 (0.58) | KDM1AKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6958678 | 0.69 | ALDH1A1 (0.62) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6958684 | 0.69 | ALDH1A1 (0.62) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714503-A | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 1998-02-03 | — | — | US | disclosed |