Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 3/20 | 0.40 |
| ▸ | GSK3B | P49841 | 3/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.40 |
| ▸ | CDK1 | P06493 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | FLT4 | P35916 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.40 |
| ▸ | CLK2 | P49760 | 2/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.40 |
| ▸ | STK3 | Q13188 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.40 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.40 |
| ▸ | HIPK4 | Q8NE63 | 2/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8687839 | 0.75 | KDM4E (0.44) | KMT2AMEN1FAAHTSHRKDM4E | |
| SCHEMBL8685466 | 0.72 | KDM1A (0.41) | KMT2AMEN1GSK3AGSK3BCDK5 | |
| SCHEMBL8685463 | 0.72 | KDM1A (0.41) | KMT2AMEN1GSK3AGSK3BCDK5 | |
| SCHEMBL6905603 | 0.70 | RAB9A (0.43) | KMT2AMEN1CDK5MAPK1TSHR | |
| SCHEMBL6958387 | 0.68 | GSK3A (0.46) | KMT2AMEN1GSK3AGSK3BCDK5 | |
| SCHEMBL9579767 | 0.65 | ALDH1A1 (0.46) | KMT2AMEN1MAPK1TSHRKDM4E | |
| SCHEMBL8892923 | 0.65 | MEN1 (0.51) | KMT2AMEN1TSHRGAAHTT | |
| SCHEMBL998965 | 0.61 | TSHR (0.49) | KMT2AMEN1CDK5TSHRKDM4E | |
| SCHEMBL15178004 | 0.61 | DEGS1 (0.54) | KDM4EGAAHSD17B10ALDH1A1RAB9A | |
| SCHEMBL45148 | 0.60 | KMT2A (0.73) | KMT2AMEN1TSHRKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714503-A | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 1998-02-03 | — | — | US | disclosed |