Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | FDFT1 | P37268 | 4/20 | 0.37 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | FADS1 | O60427 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8118267 | 0.85 | FDFT1 (0.48) | FDFT1 | |
| SCHEMBL13776051 | 0.82 | KMT2A (0.40) | KMT2ATSHRACP3GAAMEN1 | |
| SCHEMBL8110836 | 0.82 | FDFT1 (0.46) | FDFT1 | |
| SCHEMBL8319522 | 0.81 | TSHR (0.35) | KMT2ATSHRFDFT1GAAMEN1 | |
| SCHEMBL8688808 | 0.79 | KMT2A (0.38) | KMT2ATSHRGAAADRA2AADRA2B | |
| SCHEMBL8102417 | 0.78 | FDFT1 (0.49) | KMT2AFDFT1MEN1 | |
| SCHEMBL13776424 | 0.77 | HSP90AA1 (0.43) | KMT2AFDFT1MEN1RAB9APOLB | |
| SCHEMBL7237652 | 0.77 | FDFT1 (0.50) | FDFT1POLB | |
| SCHEMBL4121438 | 0.77 | MEN1 (0.46) | KMT2AACP3MEN1RAB9APOLB | |
| SCHEMBL4292426 | 0.77 | SGMS2 (0.43) | KMT2AFDFT1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770594-A | ANTICHOLESTEROL AGENTS, INHIBITORS OF CHOLESTEROL SYNTHESIS | PFIZER INC. (US) | 1998-06-23 | — | — | US | disclosed |
| WO-1996020184-A1 | NAPHTHYL-BENZOXAZEPINES OR -BENZOTHIAZEPINES AS SQUALENE SYNTHETASE INHIBITORS | PFIZER INC. (US) | 1996-07-04 | — | — | WO | disclosed |