Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8300275 | 0.85 | TP53 (0.46) | PDE4BPDE4APDE4CPDE4DPDE3B | |
| SCHEMBL8303966 | 0.84 | TP53 (0.43) | PDE4BPDE4APDE4CPDE4DPDE3B | |
| SCHEMBL8685293 | 0.82 | PDE4B (0.46) | PDE4BPDE4APDE4CPDE4DPDE3B | |
| SCHEMBL8683100 | 0.81 | PDCD1 (0.43) | PDE4BPDE4APDE4CPDE4DPDE3B | |
| SCHEMBL8300270 | 0.78 | PDE4B (0.41) | PDE4BPDE4APDE4CPDE4DPDE3B | |
| SCHEMBL8685337 | 0.76 | ALDH1A1 (0.46) | PDE4BPDE4APDE4CPDE4DPDE3B | |
| SCHEMBL8300262 | 0.76 | RAB9A (0.53) | PGRLMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL8300858 | 0.75 | ALDH1A1 (0.44) | PDE4BPDE4APDE4CPDE4DPDE3B | |
| SCHEMBL8685264 | 0.74 | TP53 (0.48) | PDE4BPDE4APDE4CPDE4DPDE3B | |
| SCHEMBL8685391 | 0.72 | TP53 (0.38) | PDE4BPDE4APDE4CPDE4DPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753642-A | AGRICULTURE, MEDICINE | ROHM AND HAAS COMPANY (US) | 1998-05-19 | — | — | US | disclosed |
| US-5728698-A | AGRICULTURAL USE, RICE, WHEAT | ROHM AND HAAS COMPANY (US) | 1998-03-17 | — | — | US | disclosed |
| US-5728715-A | FOR MAMMALS, AGRICULTURE, RICE, WHEAT, TOMATOES | ROHM AND HAAS COMPANY (US) | 1998-03-17 | — | — | US | disclosed |
| US-5728694-A | Dihydropyridazinones, pyridazinones and related compounds as fungicides | ROHM AND HAAS COMPANY (US) | 1998-03-17 | — | — | US | disclosed |
| US-5726162-A | FOR CONTROLLING AGRICULTURAL AND MAMMALIAN FUNGAL DISEASES | ROHM AND HAAS COMPANY (US) | 1998-03-10 | — | — | US | disclosed |
| US-5726176-A | FOR CONTROLLING AGRICULTURAL AND MAMMALIAN FUNGAL DISEASES | ROHM AND HAAS COMPANY (US) | 1998-03-10 | — | — | US | disclosed |
| US-5631254-A | RICE; HUMAN INFECTIONS | ROHM AND HAAS COMPANY (US) | 1997-05-20 | — | — | US | disclosed |
| US-5552409-A | PHYTOPATHOGENIC, RICE | ROHM AND HAAS COMPANY (US) | 1996-09-03 | — | — | US | disclosed |
| EP-0478195-A1 | Dihydropyridazinones, pyridazinones and related compounds as fungicides | ROHM AND HAAS COMPANY (US) | 1992-04-01 | — | — | EP | disclosed |