Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 3/20 | 0.35 |
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
| ▸ | ADH1C | P00326 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL867699 | 1.00 | CYP1A2 (0.39) | CYP1A2ADH1ASHBGADH1CCA1 | |
| SCHEMBL866107 | 1.00 | CYP1A2 (0.39) | CYP1A2ADH1ASHBGADH1CCA1 | |
| SCHEMBL868694 | 1.00 | CYP1A2 (0.39) | CYP1A2ADH1ASHBGADH1CCA1 | |
| SCHEMBL130310 | 1.00 | CYP1A2 (0.39) | CYP1A2ADH1ASHBGADH1CCA1 | |
| SCHEMBL4717621 | 1.00 | CYP1A2 (0.39) | CYP1A2ADH1ASHBGADH1CCA1 | |
| SCHEMBL22523 | 0.97 | — | — | |
| SCHEMBL866488 | 0.92 | — | — | |
| SCHEMBL1482415 | 0.87 | CYP1A2 (0.44) | CYP1A2ADH1ASHBGTSHRALDH1A1 | |
| SCHEMBL1482398 | 0.87 | CYP1A2 (0.44) | CYP1A2ADH1ASHBGTSHRALDH1A1 | |
| SCHEMBL891565 | 0.87 | CYP1A2 (0.44) | CYP1A2ADH1ASHBGTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111233786-B | Benzene sulfonamide compound containing five-membered heterocycle and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2021-11-26 | — | — | CN | claimed |
| CN-111233786-A | Benzene sulfonamide compound containing five-membered heterocycle and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2020-06-05 | — | — | CN | claimed |
| CN-110143886-B | Process for the preparation of beta-arylaminoalkols such as tulobuterol, chlorpropaline, isoadrenaline dichloride and sotalol | 北京化工大学 | 2022-11-01 | — | — | CN | disclosed |
| CN-111233786-B | Benzene sulfonamide compound containing five-membered heterocycle and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2021-11-26 | — | — | CN | disclosed |
| CN-108373420-B | Cationic surfactant, preparation method and application thereof | 中日合成化学股份有限公司 | 2020-10-20 | — | — | CN | disclosed |
| CN-111233786-A | Benzene sulfonamide compound containing five-membered heterocycle and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2020-06-05 | — | — | CN | disclosed |
| US-10059700-B2 | Supported catalyst for aldehyde coupling reaction , method for performing aldehyde coupling reaction, and method for regenerating supported catalyst for aldehyde coupling reaction | SEKISUI CHEMICAL CO., LTD. (JP) | 2018-08-28 | — | — | US | disclosed |
| US-20170112851-A1 | HEXAHYDRODIAZEPINOQUINOLINES CARRYING A SUBSTITUTED ALKYL RADICAL | AbbVie Deutschland GmbH & Co. KG (DE) | 2017-04-27 | — | — | US | disclosed |
| US-9573950-B2 | Substituted [1,4]diazepino[6,7,1-ij]quinolines as serotonin 5-HT2C receptor modulators | ABBVIE DEUTSCHLAND GMBH & CO KG (DE) | 2017-02-21 | — | — | US | disclosed |
| EP-3116873-A1 | HEXAHYDRODIAZEPINOQUINOLINES CARRYING A CYCLIC RADICAL | AbbVie Deutschland GmbH & Co. KG (DE) | 2017-01-18 | — | — | EP | disclosed |
| EP-3116874-A1 | HEXAHYDRODIAZEPINOQUINOLINES CARRYING A SUBSTITUTED ALKYL RADICAL | AbbVie Deutschland GmbH & Co. KG (DE) | 2017-01-18 | — | — | EP | disclosed |
| EP-0823423-A1 | 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-02-11 | — | — | EP | disclosed |
| EP-0457505-A2 | Pyrimidine derivatives and their use as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-11-21 | — | — | EP | disclosed |
| EP-0325397-A1 | Diurea derivatives useful as medicaments and processes for the preparation thereof | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1989-07-26 | — | — | EP | disclosed |
| US-4282171-A | Phosphorus and sulfur containing amides and thioamides | THE LUBRIZOL CORPORATION (US) | 1981-08-04 | — | — | US | disclosed |
| US-4208357-A | Process for preparing phosphorus and sulfur containing amides and thioamides | THE LUBRIZOL CORPORATION (US) | 1980-06-17 | — | — | US | disclosed |
| US-4096265-A | HYPOTENSIVE AGENTS | SHARPS ASSOCIATES (US) | 1978-06-20 | — | — | US | disclosed |
| US-4081386-A | ANTIOXIDANTS | THE LUBRIZOL CORPORATION (US) | 1978-03-28 | — | — | US | disclosed |
| US-4032461-A | PHOSPHORUS AND SULFUR CONTAINING AMIDES AND THIOAMIDES AS LUBRICATING OIL ADDITIVES AND LUBRICATING OIL COMPOSITIONS CONTAINING SAME | THE LUBRIZOL CORPORATION (US) | 1977-06-28 | — | — | US | disclosed |
| US-4031023-A | Lubricating compositions and methods utilizing hydroxy thioethers | THE LUBRIZOL CORPORATION (US) | 1977-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170112851-A1 | HEXAHYDRODIAZEPINOQUINOLINES CARRYING A SUBSTITUTED ALKYL RADICAL | HTR2C, HTR2A, HTR3C | CYP1A2 58/4885ADH1A 428/4885SHBG 1170/4885 |
| US-10059700-B2 | Supported catalyst for aldehyde coupling reaction , method for performing aldehyde coupling reaction, and method for regenerating supported catalyst for aldehyde coupling reaction | ALDH2, ALDH7A1, ALDH3A1 | CYP1A2 1715/4885ADH1A 152/4885SHBG 3737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.