Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8686279 | 1.00 | MEN1 (0.52) | MEN1KMT2ACHRM4SIGMAR1ALDH1A1 | |
| SCHEMBL8690461 | 0.91 | SLC6A12 (0.51) | MEN1KMT2ASIGMAR1ALDH1A1SLC6A12 | |
| SCHEMBL8690463 | 0.91 | SLC6A12 (0.51) | MEN1KMT2ASIGMAR1ALDH1A1SLC6A12 | |
| SCHEMBL8314184 | 0.90 | MEN1 (0.54) | MEN1KMT2ACHRM4SIGMAR1ALDH1A1 | |
| SCHEMBL8782084 | 0.90 | MEN1 (0.54) | MEN1KMT2ACHRM4SIGMAR1ALDH1A1 | |
| SCHEMBL8314188 | 0.90 | MEN1 (0.54) | MEN1KMT2ACHRM4SIGMAR1ALDH1A1 | |
| SCHEMBL8782076 | 0.90 | MEN1 (0.54) | MEN1KMT2ACHRM4SIGMAR1ALDH1A1 | |
| SCHEMBL29960364 | 0.90 | MEN1 (0.49) | MEN1KMT2ASIGMAR1ALDH1A1MAPK1 | |
| SCHEMBL8685708 | 0.89 | DRD2 (0.53) | MEN1KMT2ASIGMAR1ALDH1A1MAPK1 | |
| SCHEMBL8687558 | 0.89 | DRD2 (0.53) | MEN1KMT2ASIGMAR1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723484-A | Benzopyran compounds as 5-HT2C receptor antagonists | ADIR ET COMPAGNIE (FR) | 1998-03-03 | — | — | US | disclosed |