Aminodiphenylmethane

Aminodiphenylmethane

SCHEMBL8686295

C.NC(c1ccccc1)c1ccccc1

nearest known ligand 0.93

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Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.61
F2 P00734 1/20 0.61
HTR2A P28223 1/20 0.48
TAAR1 Q96RJ0 1/20 0.48
ADRA2A P08913 1/20 0.46
ADRA2C P18825 1/20 0.46
LMNA P02545 1/20 0.46
HIF1A Q16665 1/20 0.46
KDM4E B2RXH2 1/20 0.46
TSHR P16473 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aminodiphenylmethane SCHEMBL7841 0.97 DPP4 (0.65) DPP4F2HTR2ATAAR1ADRA2A
Aminodiphenylmethane SCHEMBL6970159 0.93 DPP4 (0.61) DPP4F2HTR2ATAAR1ADRA2A
Aminodiphenylmethane SCHEMBL2408346 0.93 DPP4 (0.61) DPP4F2HTR2ATAAR1ADRA2A
Aminodiphenylmethane SCHEMBL28527476 0.93 DPP4 (0.61) DPP4F2HTR2ATAAR1ADRA2A
Aminodiphenylmethane SCHEMBL9596876 0.93 DPP4 (0.61) DPP4F2HTR2ATAAR1ADRA2A
SCHEMBL11480062 0.93 DPP4 (0.61) DPP4F2HTR2ATAAR1ADRA2A
Aminodiphenylmethane SCHEMBL8518249 0.93 DPP4 (0.61) DPP4F2HTR2ATAAR1ADRA2A
SCHEMBL11478580 0.93 DPP4 (0.61) DPP4F2HTR2ATAAR1ADRA2A
Aminodiphenylmethane SCHEMBL1764753 0.93 DPP4 (0.61) DPP4F2HTR2ATAAR1ADRA2A
Aminodiphenylmethane SCHEMBL28037935 0.90 DPP4 (0.58) DPP4F2HTR2ATAAR1ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5847169-A Process for preparing oxiranemethanamine derivatives BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 1998-12-08 US disclosed