SCHEMBL8686393

SCHEMBL8686393

COC(=O)/C=C/C(=O)OCC1CO1

nearest known ligand 0.49

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 3/20 0.49
ALDH1A1 P00352 2/20 0.49
HCAR2 Q8TDS4 2/20 0.48
KEAP1 Q14145 1/20 0.48
NFE2L2 Q16236 1/20 0.48
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4948009 1.00 MGLL (0.49) MGLLALDH1A1HCAR2KEAP1NFE2L2
SCHEMBL4948022 1.00 MGLL (0.49) MGLLALDH1A1HCAR2KEAP1NFE2L2
SCHEMBL624267 0.90 MGLL (0.55) MGLLALDH1A1TP53CYP3A4
SCHEMBL268634 0.90 MGLL (0.55) MGLLALDH1A1TP53CYP3A4
SCHEMBL268635 0.90 MGLL (0.55) MGLLALDH1A1TP53CYP3A4
SCHEMBL1286819 0.85 HCAR2 (0.52) MGLLALDH1A1HCAR2TP53CYP3A4
SCHEMBL1286817 0.85 HCAR2 (0.52) MGLLALDH1A1HCAR2TP53CYP3A4
SCHEMBL8054471 0.85 HCAR2 (0.52) MGLLALDH1A1HCAR2TP53CYP3A4
Ethane SCHEMBL2120677 0.84 MGLL (0.51) MGLLALDH1A1HCAR2TP53CYP3A4
SCHEMBL422856 0.83 MGLL (0.54) MGLLALDH1A1HCAR2TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10179835-B2 Radical crosslinking of polyether carbonate polyols that have electron-poor and electron-rich double bonds COVESTRO DEUTSCHLAND AG (DE) 2019-01-15 US disclosed
US-20160200865-A1 RADICAL CROSSLINKING OF POLYETHER CARBONATE POLYOLS THAT HAVE ELECTRON-POOR AND ELECTRON-RICH DOUBLE BONDS COVESTRO DEUTSCHLAND AG (DE) 2016-07-14 US disclosed
CN-1957024-A Particle with rough surface and process for producing the same NISSHIN SPINNING (JP) 2007-05-02 CN disclosed
CN-1957023-A Particle with rough surface for plating or vapor deposition NISSHIN SPINNING (JP) 2007-05-02 CN disclosed
CN-1681871-A Flaky particles and process for production thereof NISSHIN SPINNING (JP) 2005-10-12 CN disclosed
CN-1073137-C curable resin composition for water-based paint DAINIPPON INK & CHEMICALS (JP) 2001-10-17 CN disclosed
US-5811492-A HAVING EXCELLENT HEAT, FIRE, CHEMICAL AND IMPACT RESISTANCE, MECHANICAL STRENGTH, AND MOLDABILITY; CONTAINING AMINO GROUPS, HYDROGENATED BLOCK COPOLYMER AND A POLYAMIDE RESIN GENERAL ELECTRIC COMPANY (US) 1998-09-22 US disclosed
CN-1178546-A Curable resin composition for water-based paints DAINIPPON INK & CHEMICALS (JP) 1998-04-08 CN disclosed
US-5523358-A REACTING POLYOLEFIN WITH ETHYLENICALLY UNSATURATED COMPOUND IN THE PRESENCE OF FREE RADICAL INITIATOR MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-06-04 US disclosed
EP-0370753-B1 Modified polyolefin particles and process for preparation thereof MITSUI PETROCHEMICAL IND (JP) 1995-01-18 EP disclosed
EP-0370753-A2 Modified polyolefin particles and process for preparation thereof MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1990-05-30 EP disclosed