Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 5/20 | 0.61 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.61 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18550734 | 0.86 | GAA (0.63) | AKR1C3AKR1C2RAPGEF4GAAMEN1 | |
| SCHEMBL1921497 | 0.82 | MEN1 (0.62) | AKR1C3AKR1C2RAPGEF4GAAMEN1 | |
| SCHEMBL13890897 | 0.81 | EGFR (0.55) | AKR1C3AKR1C2GAAMAPTPOLB | |
| SCHEMBL1085867 | 0.81 | MEN1 (0.71) | AKR1C3AKR1C2RAPGEF4GAAMEN1 | |
| SCHEMBL26908423 | 0.81 | RAPGEF4 (0.55) | AKR1C3AKR1C2RAPGEF4GAAMEN1 | |
| SCHEMBL21883722 | 0.80 | RAPGEF4 (0.67) | AKR1C3AKR1C2RAPGEF4GAAMEN1 | |
| SCHEMBL30939891 | 0.80 | PTGS1 (0.64) | AKR1C3AKR1C2RAPGEF4GAAMEN1 | |
| SCHEMBL28041521 | 0.80 | PTGS1 (0.64) | AKR1C3AKR1C2RAPGEF4GAAMEN1 | |
| SCHEMBL13302353 | 0.79 | MEN1 (0.69) | AKR1C3AKR1C2RAPGEF4GAAMEN1 | |
| SCHEMBL2112594 | 0.78 | KMT2A (0.71) | AKR1C3AKR1C2RAPGEF4GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723295-A | MULTISTAGE CHEMILUMINESCENT ASSAY WITH PEROXIDASE ENZYME, PH ADJUSTMENT | LUMIGEN, INC. (US) | 1998-03-03 | — | — | US | disclosed |
| US-5670644-A | CHEMILUMINESCENT REACTIONS, PEROXIDASE AND PH FOR IMMUNOASSAY | LUMIGEN, INC. (US) | 1997-09-23 | — | — | US | disclosed |