SCHEMBL1921497

SCHEMBL1921497

COc1cccc(Nc2ccccc2Nc2cccc(OC)c2)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.62
KMT2A Q03164 3/20 0.62
MAPT P10636 1/20 0.62
MAPK1 P28482 1/20 0.62
POLB P06746 1/20 0.62
AKR1C3 P42330 2/20 0.59
AKR1C2 P52895 2/20 0.59
HTT P42858 2/20 0.59
TSHR P16473 1/20 0.59
RAPGEF4 Q8WZA2 1/20 0.59
ABCG2 Q9UNQ0 2/20 0.56
ABCB1 P08183 1/20 0.56
GAA P10253 2/20 0.56
MTNR1A P48039 1/20 0.54
MTNR1B P49286 1/20 0.54
NPC1 O15118 3/20 0.54
GFER P55789 1/20 0.54
RAB9A P51151 3/20 0.53
EGFR P00533 2/20 0.53
ALDH1A1 P00352 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18550734 0.89 GAA (0.63) MEN1KMT2AMAPTMAPK1POLB
SCHEMBL4945734 0.88 GAA (0.66) MEN1KMT2AMAPTMAPK1POLB
SCHEMBL6354623 0.88 RAB9A (0.55) MEN1KMT2AMAPTMAPK1POLB
SCHEMBL6352626 0.88 L3MBTL1 (0.55) MEN1KMT2AMAPTMAPK1POLB
SCHEMBL1085867 0.87 MEN1 (0.71) MEN1KMT2AMAPTMAPK1POLB
SCHEMBL917608 0.86 MTNR1B (0.65) MEN1KMT2AMAPTMAPK1POLB
SCHEMBL30080139 0.86 MTNR1B (0.65) MEN1KMT2AMAPTMAPK1POLB
SCHEMBL13302353 0.85 MEN1 (0.69) MEN1KMT2AMAPTMAPK1POLB
SCHEMBL9479511 0.84 MTNR1B (0.68) MEN1KMT2AMAPTMAPK1POLB
SCHEMBL9479608 0.84 MTNR1B (0.68) MEN1KMT2AMAPTMAPK1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1528074-B1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF TOSOH CORP (JP) 2014-03-26 EP disclosed
EP-2327739-A1 Novel triarylamine polymer, process for its production and its use TOSOH CORPORATION (JP) 2011-06-01 EP disclosed
US-7608680-B2 Triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2009-10-27 US disclosed
US-20070282076-A1 Transition Metal Carbene Complexes Embedded in Polymer Matrices for Use in Oleds BASF AKTIENGESELLSCHAFT (DE) 2007-12-06 US disclosed
US-20070282076-A1 Transition Metal Carbene Complexes Embedded in Polymer Matrices for Use in Oleds BASF AKTIENGESELLSCHAFT (DE) 2007-12-06 US disclosed
US-20060241278-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2006-10-26 US disclosed
US-20060017040-A9 Novel triarylamine polymer, process for producing the same, and use thereof SUZUKI TAKAO 2006-01-26 US disclosed
EP-1528074-A1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Tosoh Corporation (JP) 2005-05-04 EP disclosed
US-20040262574-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2004-12-30 US disclosed
US-6034206-A POLYANILINES; HEAT, CHEMICAL AND SOLVENT RESISTANCE TOSOH CORPORATION (JP) 2000-03-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070282076-A1 Transition Metal Carbene Complexes Embedded in Polymer Matrices for Use in Oleds OCIAD1, OCIAD2, PPID MEN1 4316/4885KMT2A 3145/4885MAPT 525/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.