Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.44 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8682285 | 0.82 | SLC22A12 (0.44) | SLC22A12SLC16A3MEN1KMT2AGAA | |
| SCHEMBL1553851 | 0.81 | SLC22A12 (0.58) | SLC22A12MEN1KMT2AGAARAB9A | |
| SCHEMBL7656202 | 0.81 | KDM4E (0.38) | KMT2AGAARAB9AALDH1A1HPGD | |
| SCHEMBL8683774 | 0.79 | SLC16A3 (0.41) | SLC22A12SLC16A3MEN1KMT2AGAA | |
| SCHEMBL24725790 | 0.78 | CNR1 (0.52) | SLC16A3RAB9ACNR2F2RL3HDAC3 | |
| SCHEMBL14977876 | 0.76 | F2RL3 (0.48) | SLC16A3MEN1KMT2AGAARAB9A | |
| SCHEMBL16127813 | 0.74 | GAA (0.52) | SLC22A12MEN1KMT2AGAARAB9A | |
| SCHEMBL17608582 | 0.72 | F2RL3 (0.45) | SLC16A3MEN1KMT2AGAARAB9A | |
| SCHEMBL1553752 | 0.72 | GAA (0.52) | MEN1KMT2AGAARAB9AF2RL3 | |
| SCHEMBL30614183 | 0.71 | RECQL (0.54) | MEN1KMT2AGAARAB9AMAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760028-A | TREATING CANCER METASTASIS, DIABETIC RETINOPATHY, NEOVASCULAR GLAUCOMA, THROMBOSIS, RESTENOSIS, OSTEOPOROSIS, MACULAR DEGENERATION | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-06-02 | — | — | US | disclosed |