Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.39 |
| ▸ | ITGAV | P06756 | 5/20 | 0.39 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8682759 | 0.86 | ITGB3 (0.40) | ITGB3ITGAVITGB5GAARAB9A | |
| SCHEMBL8687237 | 0.79 | SLC22A12 (0.44) | SLC16A3SLC22A12MEN1KMT2AGAA | |
| SCHEMBL4958032 | 0.78 | CSNK2A2 (0.43) | SLC22A12ITGB3ITGAVITGB5ITGB1 | |
| SCHEMBL8682285 | 0.76 | SLC22A12 (0.44) | SLC16A3SLC22A12MEN1KMT2AGAA | |
| SCHEMBL1553851 | 0.75 | SLC22A12 (0.58) | SLC22A12MEN1KMT2AGAARAB9A | |
| SCHEMBL14977876 | 0.70 | F2RL3 (0.48) | SLC16A3MEN1KMT2AGAARAB9A | |
| SCHEMBL16127813 | 0.69 | GAA (0.52) | SLC22A12MEN1KMT2AGAARAB9A | |
| SCHEMBL7030784 | 0.68 | ITGB3 (0.52) | ITGB3ITGAVITGB5ITGB1ITGB6 | |
| SCHEMBL7414619 | 0.67 | SLC22A12 (0.46) | SLC22A12MEN1KMT2AGAAKDM4E | |
| SCHEMBL8682252 | 0.67 | KDM4E (0.42) | ITGB3ITGAVMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760028-A | TREATING CANCER METASTASIS, DIABETIC RETINOPATHY, NEOVASCULAR GLAUCOMA, THROMBOSIS, RESTENOSIS, OSTEOPOROSIS, MACULAR DEGENERATION | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-06-02 | — | — | US | disclosed |