SCHEMBL8687331

SCHEMBL8687331

O=C(O)COCc1ccsc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 2/20 0.51
SLC1A2 P43004 2/20 0.51
SLC1A1 P43005 2/20 0.51
L3MBTL1 Q9Y468 1/20 0.42
MAPT P10636 1/20 0.40
KMT2A Q03164 1/20 0.40
LCK P06239 1/20 0.39
FYN P06241 1/20 0.39
DAO P14920 1/20 0.39
HCAR3 P49019 1/20 0.39
HCAR2 Q8TDS4 1/20 0.39
KDM4C Q9H3R0 1/20 0.39
TAAR1 Q96RJ0 1/20 0.38
PARP15 Q460N3 1/20 0.38
PARP10 Q53GL7 1/20 0.38
PARP3 Q9Y6F1 1/20 0.38
PTPN1 P18031 1/20 0.38
LTA4H P09960 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20912452 0.82 TAAR1 (0.44) SLC1A3SLC1A2SLC1A1L3MBTL1MAPT
SCHEMBL20912421 0.82 SLC1A3 (0.49) SLC1A3SLC1A2SLC1A1L3MBTL1LCK
SCHEMBL6781821 0.82 SLC1A3 (0.46) SLC1A3SLC1A2SLC1A1L3MBTL1MAPT
SCHEMBL20912422 0.80 SLC1A3 (0.47) SLC1A3SLC1A2SLC1A1LTA4HHDAC8
SCHEMBL20912423 0.78 SLC1A3 (0.46) SLC1A3SLC1A2SLC1A1MAPTLTA4H
SCHEMBL9257247 0.78 CYP1A2 (0.48) SLC1A3SLC1A2SLC1A1L3MBTL1CYP1A2
SCHEMBL351615 0.74
SCHEMBL231282 0.74 TSHR (0.61) L3MBTL1MAPTKMT2A
SCHEMBL8689058 0.73 SLC1A3 (0.42) SLC1A3SLC1A2SLC1A1KMT2ATAAR1
SCHEMBL8687460 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11269251-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-03-08 US disclosed
CN-106831614-B Substituted benzodiazacyclo compound and its preparation method and use 清华大学 2020-07-28 CN disclosed
US-20190113844-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2019-04-18 US disclosed
US-5807871-A PSYCHOLOGICAL DISORDERS, ALZHEIMER OR PARKINSON DISEASE H. LUNDBECK A/S (DK) 1998-09-15 US disclosed
US-5439932-A Anticholesterol agents BANYU PHARMACEUTICAL CO., LTD. (JP) 1995-08-08 US disclosed
US-5306728-A Substituted amine derivatives having antihyperlipemia activity BANYU PHARMACEUTICAL CO., LTD. (JP) 1994-04-26 US disclosed
EP-0448078-A2 Substituted amine derivatives having anti-hyperlipemia activity BANYU PHARMACEUTICAL CO., LTD. (JP) 1991-09-25 EP disclosed