Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 6/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.50 |
| ▸ | MC3R | P41968 | 1/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.50 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.50 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 4/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.48 |
| ▸ | TNF | P01375 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8952947 | 1.00 | ADORA2B (0.50) | ADORA2BADORA2AACHEPIK3CDPOLB | |
| SCHEMBL7936399 | 0.99 | ADORA2B (0.51) | ADORA2BADORA2AACHEPIK3CDPOLB | |
| SCHEMBL21708442 | 0.94 | ADORA2B (0.45) | ADORA2BADORA2AACHEPIK3CDPOLB | |
| SCHEMBL8802951 | 0.90 | ADORA2B (0.50) | ADORA2BADORA2AACHEPIK3CDPOLB | |
| SCHEMBL27348726 | 0.86 | ADORA2B (0.51) | ADORA2BADORA2AACHEPIK3CDPOLB | |
| SCHEMBL27334770 | 0.86 | ADORA2B (0.51) | ADORA2BADORA2AACHEPIK3CDPOLB | |
| SCHEMBL7199494 | 0.86 | ADORA2B (0.48) | ADORA2BADORA2AACHEPIK3CDPOLB | |
| SCHEMBL5475807 | 0.85 | ADORA2B (0.45) | ADORA2BADORA2AACHEPIK3CDPOLB | |
| SCHEMBL2036205 | 0.85 | ADORA2B (0.45) | ADORA2BADORA2AACHEPIK3CDPOLB | |
| SCHEMBL8378553 | 0.85 | ADORA2B (0.45) | ADORA2BADORA2AACHEPIK3CDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770595-A | Oxime substituted therapeutic compounds | CELL THERAPEUTICS, INC. (US) | 1998-06-23 | — | — | US | disclosed |
| WO-1994016704-A1 | OXIME-SUBSTITUTED THERAPEUTIC COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1994-08-04 | — | — | WO | disclosed |