Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 6/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.45 |
| ▸ | MC3R | P41968 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.45 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.45 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 4/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.44 |
| ▸ | TNF | P01375 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2036205 | 1.00 | ADORA2B (0.45) | ADORA2BADORA2AACHEPOLBPIK3CD | |
| SCHEMBL8378553 | 1.00 | ADORA2B (0.45) | ADORA2BADORA2AACHEPOLBPIK3CD | |
| SCHEMBL8921217 | 0.99 | ADORA2B (0.44) | ADORA2BADORA2AACHEPOLBPIK3CD | |
| SCHEMBL8687550 | 0.85 | ADORA2B (0.50) | ADORA2BADORA2AACHEPOLBPIK3CD | |
| SCHEMBL8952947 | 0.85 | ADORA2B (0.50) | ADORA2BADORA2AACHEPOLBPIK3CD | |
| SCHEMBL7936399 | 0.84 | ADORA2B (0.51) | ADORA2BADORA2AACHEPOLBPIK3CD | |
| SCHEMBL8077198 | 0.83 | ADORA2B (0.62) | ADORA2BADORA2AACHEPDE4APDE4B | |
| SCHEMBL6785565 | 0.83 | ADORA2B (0.62) | ADORA2BADORA2AACHEPDE4APDE4B | |
| SCHEMBL8919125 | 0.83 | TSHR (0.46) | ADORA2BADORA2AACHEPOLBPIK3CD | |
| SCHEMBL8978234 | 0.82 | ADORA2B (0.41) | ADORA2BADORA2AACHEPOLBPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11879012-B2 | Method of modulating cell proliferation | GILLIES, Peter (AU) | 2024-01-23 | — | — | US | disclosed |
| US-20200407451-A1 | A METHOD OF MODULATING CELL PROLIFERATION | Metro North Hospital and Health Service (AU) | 2020-12-31 | — | — | US | disclosed |
| US-20070105939-A1 | Mesylate salt of 5-(2-dimethylaminoethoxy)-1H-indole-2-carboxylic acid [3-(4-hydroxycarbamoylphenyl)prop-2-ynyl]amide | PHARMACYCLICS, INC. (US) | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105939-A1 | Mesylate salt of 5-(2-dimethylaminoethoxy)-1H-indole-2-carboxylic acid [3-(4-hydroxycarbamoylphenyl)prop-2-ynyl]amide | HTR5A, HTR2B, HTR2A | ADORA2B 86/4885ADORA2A 233/4885ACHE 2746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.