Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8686386 | 0.79 | HPGD (0.38) | HPGDKMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL8687636 | 0.77 | ADRB3 (0.36) | CNR2KMT2AMEN1KDM4EMAPK1 | |
| SCHEMBL8685055 | 0.76 | MAPK14 (0.43) | HPGDHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL8690619 | 0.73 | IGF1R (0.40) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL8686336 | 0.73 | TUBB4A (0.34) | HTR1AHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL8685374 | 0.73 | PIM1 (0.36) | HDAC1HDAC2DHPSTUBB4ATUBB | |
| SCHEMBL8686689 | 0.73 | HPGDS (0.41) | HPGDCNR2KMT2AALDH1A1CYP1A2 | |
| SCHEMBL8686452 | 0.72 | MEN1 (0.37) | HPGDKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL8687931 | 0.71 | PTGER3 (0.35) | LMNAHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL8686631 | 0.71 | MAPK14 (0.37) | CNR1KMT2AMEN1MAPTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811439-A | ANTIDIABETIC AGENTS; SIDE EFFECT REDUCTION; ANTILEPEMIC AGENTS | SENGA PHARMACEUTICAL LABORATORY INC. (JP) | 1998-09-22 | — | — | US | disclosed |