Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 6/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 13/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 13/20 | 0.40 |
| ▸ | PDE4A | P27815 | 7/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8688278 | 0.86 | TNF (0.43) | TNFPDE4BPDE4CPDE4APDE4D | |
| SCHEMBL8690592 | 0.80 | RECQL (0.33) | PDE4BPDE4CPDE4APDE4DRECQL | |
| SCHEMBL8695650 | 0.80 | FDPS (0.44) | — | |
| SCHEMBL8688277 | 0.79 | PDE4B (0.41) | TNFPDE4BPDE4CPDE4APDE4D | |
| SCHEMBL8688145 | 0.79 | PDE4B (0.40) | TNFPDE4BPDE4CPDE4APDE4D | |
| SCHEMBL8688274 | 0.78 | PDE4B (0.41) | TNFPDE4BPDE4CPDE4APDE4D | |
| SCHEMBL8688141 | 0.77 | PDE4B (0.40) | TNFPDE4BPDE4CPDE4APDE4D | |
| SCHEMBL9364664 | 0.73 | PDE4B (0.45) | TNFPDE4BPDE4CPDE4APDE4D | |
| SCHEMBL8690107 | 0.68 | PDE4B (0.33) | PDE4BPDE4CPDE4APDE4DRECQL | |
| SCHEMBL8695647 | 0.65 | FDPS (0.41) | PDE4BPDE4CPDE4APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710147-A | ANTIBIOTICS | ROUSSEL UCLAF (FR) | 1998-01-20 | — | — | US | disclosed |