Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 13/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 13/20 | 0.45 |
| ▸ | PDE4A | P27815 | 7/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.45 |
| ▸ | TNF | P01375 | 9/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9361830 | 0.84 | RARG (0.36) | PDE4BPDE4CTNF | |
| SCHEMBL8435541 | 0.80 | RARG (0.37) | PDE4BPDE4CPDE4APDE4DTNF | |
| SCHEMBL9364780 | 0.80 | FDPS (0.39) | — | |
| SCHEMBL9364775 | 0.80 | FDPS (0.39) | — | |
| SCHEMBL9362238 | 0.80 | RARG (0.38) | PDE4BPDE4CPDE4APDE4DTNF | |
| SCHEMBL8688274 | 0.75 | PDE4B (0.41) | PDE4BPDE4CPDE4APDE4DTNF | |
| SCHEMBL8688278 | 0.75 | TNF (0.43) | PDE4BPDE4CPDE4APDE4DTNF | |
| SCHEMBL8688277 | 0.75 | PDE4B (0.41) | PDE4BPDE4CPDE4APDE4DTNF | |
| SCHEMBL8688141 | 0.73 | PDE4B (0.40) | PDE4BPDE4CPDE4APDE4DTNF | |
| SCHEMBL8688151 | 0.73 | TNF (0.42) | PDE4BPDE4CPDE4APDE4DTNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0241901-B1 | Cephalosporin derivatives, processes for their preparation and antibacterial agents | BANYU PHARMA CO LTD (JP) | 1994-08-24 | — | — | EP | disclosed |
| US-5061794-A | Effective against pseudomonads | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-10-29 | — | — | US | disclosed |
| US-4988687-A | Thiazoleoxyimineacetamido carboxymethylpyridinium derivatives of cephalosporins | BANYU PHARMACEUTICAL COMPANY, LTD. (JP) | 1991-01-29 | — | — | US | disclosed |
| US-4880797-A | THIAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-11-14 | — | — | US | disclosed |
| EP-0241901-A2 | Cephalosporin derivatives, processes for their preparation and antibacterial agents | Banyu Pharmaceutical Co., Ltd. (JP) | 1987-10-21 | — | — | EP | disclosed |
| EP-0238061-A2 | Cephalosporin derivatives, processes for their preparation and antibacterial agents | Banyu Pharmaceutical Co., Ltd. (JP) | 1987-09-23 | — | — | EP | disclosed |