⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27442584 | 0.93 | FAAH (0.48) | — | |
| SCHEMBL28474044 | 0.91 | FAAH (0.52) | — | |
| SCHEMBL28485780 | 0.91 | FAAH (0.52) | — | |
| SCHEMBL899170 | 0.86 | — | — | |
| SCHEMBL20996668 | 0.81 | TSHR (0.42) | — | |
| SCHEMBL24864621 | 0.79 | CNR1 (0.39) | — | |
| SCHEMBL3190096 | 0.79 | — | — | |
| SCHEMBL2195544 | 0.77 | GPR84 (0.31) | — | |
| SCHEMBL27313766 | 0.77 | — | — | |
| SCHEMBL36083 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100460402-C | Therapeutic benzopyranone compounds used as intermediates. | ASTRAZENECA AB (SE) | 2009-02-11 | — | — | CN | disclosed |
| CN-100384833-C | Therapeutic chroman compounds | ASTRAZENECA AB (SE) | 2008-04-30 | — | — | CN | disclosed |
| CN-1740168-A | Therapeutic benzopyranone compounds used as intermediates. | ASTRAZENECA AB (SE) | 2006-03-01 | — | — | CN | disclosed |
| CN-1592745-A | Therapeutic chromone compounds | ASTRAZENECA AB (SE) | 2005-03-09 | — | — | CN | disclosed |
| CN-1524077-A | Therapeutic chroman compounds | — | 2004-08-25 | — | — | CN | disclosed |
| US-5792399-A | FIBER OR FOIL MOLDINGS; FUNGISTATIC PROPERTIES, ANION EXCHANGE CAPACITIES | OSTTHURINGISCHE MATERIALPRUFGESELLSCHAFT FUR TEXTIL UND KUNSTSTOFFE MBH (DE) | 1998-08-11 | — | — | US | disclosed |