SCHEMBL8688728

SCHEMBL8688728

O=C(O)c1ccnc(Cl)c1.O=C(O)c1ccncc1Br

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 8/20 0.41
KDM4A O75164 5/20 0.41
KDM4E B2RXH2 4/20 0.41
KDM5C P41229 4/20 0.41
KDM6B O15054 3/20 0.41
KDM4D Q6B0I6 3/20 0.41
KDM5B Q9UGL1 3/20 0.41
KDM2A Q9Y2K7 3/20 0.41
KDM3A Q9Y4C1 3/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPT P10636 2/20 0.41
KDM5A P29375 2/20 0.41
TET3 O43151 1/20 0.41
BBOX1 O75936 1/20 0.41
ASPH Q12797 1/20 0.41
TET2 Q6N021 1/20 0.41
ALKBH5 Q6P6C2 1/20 0.41
KDM7A Q6ZMT4 1/20 0.41
KDM8 Q8N371 1/20 0.41
TET1 Q8NFU7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isonicotinic Acid SCHEMBL28210508 0.80 NAPRT (0.63) KDM4CKDM4AKDM4EKDM5CKDM6B
SCHEMBL40123 0.80 KDM4C (0.61) KDM4CKDM4AKDM4EKDM5CKDM6B
SCHEMBL29920601 0.80 KDM4C (0.59) KDM4CKDM4AKDM4EKDM6BKDM4D
SCHEMBL480991 0.80 KDM4C (0.59) KDM4CKDM4AKDM4EKDM6BKDM4D
Hydrochloric Acid SCHEMBL7221156 0.78 KDM4C (0.59) KDM4CKDM4AKDM4EKDM5CKDM6B
Bromide SCHEMBL7842108 0.78 KDM4C (0.59) KDM4CKDM4AKDM4EKDM5CKDM6B
Hydrochloric Acid SCHEMBL2892062 0.78 KDM4C (0.57) KDM4CKDM4AKDM4EKDM6BKDM4D
Methane SCHEMBL9122275 0.78 KDM5C (0.59) KDM4CKDM4AKDM4EKDM5CKDM6B
SCHEMBL31547893 0.78 KDM4C (0.59) KDM4CKDM4AKDM4EKDM5CKDM6B
Hydrogen Sulfide SCHEMBL27953098 0.74 KDM5C (0.53) KDM4CKDM4AKDM4EKDM5CKDM6B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5710278-A Herbicidal 1-pyridyltetrazolinones NIHON BAYER AGROCHEM K.K. (JP) 1998-01-20 US disclosed