SCHEMBL8688802

SCHEMBL8688802

CC(N)(CCCCC(C)(N)C(=O)O)C(=O)O

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ARG2 P78540 7/20 0.72
ARG1 P05089 6/20 0.72
GGT1 P19440 1/20 0.60
TDP1 Q9NUW8 2/20 0.42
FFAR1 O14842 1/20 0.42
CPT2 P23786 1/20 0.42
BLM P54132 2/20 0.42
ACLY P53396 1/20 0.41
ACACB O00763 1/20 0.40
ACACA Q13085 1/20 0.40
ALDH1A1 P00352 3/20 0.38
MEN1 O00255 2/20 0.38
CYP1A2 P05177 2/20 0.38
KMT2A Q03164 2/20 0.38
KDM4E B2RXH2 1/20 0.38
USP2 O75604 1/20 0.38
EGFR P00533 1/20 0.38
FYN P06241 1/20 0.38
POLB P06746 1/20 0.38
CYP3A4 P08684 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11513176 0.91 ARG1 (0.62) ARG2ARG1GGT1TDP1ALDH1A1
SCHEMBL22518917 0.91 ARG1 (0.62) ARG2ARG1GGT1TDP1ALDH1A1
SCHEMBL201390 0.91 ARG1 (0.62) ARG2ARG1GGT1TDP1FFAR1
SCHEMBL18646645 0.91 ARG1 (0.62) ARG2ARG1GGT1TDP1ALDH1A1
SCHEMBL574473 0.91 ARG1 (0.62) ARG2ARG1GGT1TDP1FFAR1
SCHEMBL498228 0.91 ARG2 (0.62) ARG2ARG1GGT1TDP1FFAR1
SCHEMBL161423 0.91 ARG1 (0.62) ARG2ARG1GGT1TDP1FFAR1
SCHEMBL23733387 0.89 ARG1 (0.60) ARG2ARG1GGT1TDP1FFAR1
SCHEMBL7182094 0.89 ARG1 (0.60) ARG2ARG1GGT1TDP1FFAR1
SCHEMBL5325205 0.89 ARG1 (0.60) ARG2ARG1GGT1TDP1FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5731289-A BRIDGED DIPEPTIDE COMPOUNDS WHICH HAVE A STIMULATING ACTIVITY ON CELL DIVISION, ESPECIALLY IN MYELOPOIETIC AND BONE MARROW CELLS NYCOMED IMAGING AS (NO) 1998-03-24 US disclosed
EP-0731810-A1 DOUBLE-CHAIN HEMOREGULATORY PEPTIDES NYCOMED IMAGING AS (NO) 1996-09-18 EP disclosed
WO-1995015336-A1 DOUBLE-CHAIN HEMOREGULATORY PEPTIDES NYCOMED IMAGING AS (NO) 1995-06-08 WO disclosed