Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 11/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8688630 | 0.89 | PTGS2 (0.55) | F10PTGS2PTGS1 | |
| SCHEMBL8688474 | 0.89 | PTGS2 (0.47) | F10PTGS2PTGS1 | |
| SCHEMBL8689482 | 0.83 | PTGS2 (0.67) | F10PTGS2PTGS1 | |
| SCHEMBL8693434 | 0.82 | PTGS2 (0.53) | F10PTGS2PTGS1 | |
| SCHEMBL6351481 | 0.82 | PTGS2 (0.73) | PTGS2PTGS1 | |
| SCHEMBL8691651 | 0.81 | PTGS2 (0.49) | F10PTGS2PTGS1 | |
| SCHEMBL8693951 | 0.81 | PTGS2 (0.55) | F10PTGS2PTGS1 | |
| SCHEMBL8689004 | 0.81 | PTGS2 (0.68) | F10PTGS2PTGS1 | |
| SCHEMBL8638981 | 0.80 | F10 (0.48) | F10PTGS2PTGS1 | |
| SCHEMBL8689419 | 0.80 | PTGS2 (0.47) | F10PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760068-A | NONSTEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G.D. SEARLE & CO. (US) | 1998-06-02 | — | — | US | disclosed |
| US-5756529-A | ANTIINFLAMMATORY | G.D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |