SCHEMBL868944

SCHEMBL868944

C=C(C)C(=O)OCCCN(CCCC)CCCC

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.68
THRB P10828 2/20 0.50
LMNA P02545 1/20 0.48
CYP1A2 P05177 1/20 0.48
CHRM2 P08172 1/20 0.48
CYP3A4 P08684 1/20 0.48
HTR1A P08908 1/20 0.48
GAA P10253 1/20 0.48
CYP2D6 P10635 1/20 0.48
DRD3 P35462 1/20 0.48
SCN1A P35498 1/20 0.48
SLC6A3 Q01959 1/20 0.48
KCNH2 Q12809 1/20 0.48
SCN2A Q99250 1/20 0.48
SCN3A Q9NY46 1/20 0.48
ALDH1A1 P00352 2/20 0.44
POLB P06746 1/20 0.41
APEX1 P27695 1/20 0.41
HTT P42858 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28432695 0.95 TSHR (0.71) TSHRTHRBLMNACYP1A2CHRM2
SCHEMBL2830555 0.95 TSHR (0.71) TSHRTHRBLMNACYP1A2CHRM2
SCHEMBL28679639 0.93 TSHR (0.74) TSHRTHRBLMNACYP1A2CHRM2
SCHEMBL222109 0.93 TSHR (0.62) TSHRTHRBLMNACYP1A2CHRM2
SCHEMBL345336 0.93 TSHR (0.62) TSHRTHRBLMNACYP1A2CHRM2
SCHEMBL28346965 0.93 TSHR (0.60) TSHRTHRBLMNACYP1A2CHRM2
SCHEMBL1336680 0.90 TSHR (0.80) TSHRTHRBLMNACYP1A2CHRM2
SCHEMBL15178914 0.90 TSHR (0.64) TSHRTHRBLMNACYP1A2CHRM2
SCHEMBL11223664 0.90 TSHR (0.80) TSHRTHRBLMNACYP1A2CHRM2
SCHEMBL28191952 0.88 TSHR (0.54) TSHRTHRBLMNACYP1A2CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109535973-B Two-component aqueous polyurethane coating composition with thixotropic flow characteristic and preparation method thereof 中国海洋石油集团有限公司 2021-07-09 CN claimed
CN-109554048-B Baking type water-based acrylic acid middle coating composition with anti-sagging characteristic and preparation method thereof 中国海洋石油集团有限公司 2021-01-19 CN claimed
CN-109554093-B Two-component waterborne polyurethane floating coating composition with anti-sagging characteristic and preparation method thereof 中国海洋石油集团有限公司 2020-12-11 CN claimed
CN-109608970-B Baking type water-based acrylic coating composition with excellent thixotropy and preparation method thereof 中国海洋石油集团有限公司 2020-10-16 CN claimed
US-5047287-A Acrylonitrile-isoprene or butadiene/1,3-/ copolymer having amino group as adhesive TOYODA GOSEI CO., LTD. (JP) 1991-09-10 US claimed
US-4751277-A OIL-RESISTANT RUBBER JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1988-06-14 US claimed
US-4091165-A COATING OF A POLYMER OF AMINOALKYL ACRYLATE, ALKYL ACRYLATE AND VINYL MONOMER TREATED WITH HALOACETIC ACID SALT MITSUBISHI PETROCHEMICAL CO., LTD. (JA) 1978-05-23 US claimed
CN-108602921-B Finely divided cationic aqueous polymer dispersions, method for the production thereof and use thereof 巴斯夫欧洲公司 2021-05-07 CN disclosed
US-10975525-B2 Finely divided, cationic, aqueous polymer dispersions, method for the production thereof, and the use thereof SOLENIS TECHNOLOGIES, L.P. (US) 2021-04-13 US disclosed
EP-3478734-B1 FINELY DIVIDED, CATIONIC, AQUEOUS POLYMER DISPERSIONS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF SOLENIS TECHNOLOGIES CAYMAN LP (KY) 2021-03-31 EP disclosed
EP-3383929-B1 FINELY DIVIDED, CATIONIC, AQUEOUS POLYMER DISPERSIONS, METHOD FOR THE PRODUCTION THEREOF, AND THE USE THEREOF SOLENIS TECHNOLOGIES CAYMAN LP (KY) 2020-11-04 EP disclosed
EP-2217827-B1 SUSPENSION SYSTEM FOR AIRCRAFT AUXILIARY POWER UNIT WITH ELASTOMERIC MEMBER LORD CORP (US) 2020-06-03 EP disclosed
EP-3478734-A1 FINELY DIVIDED, CATIONIC, AQUEOUS POLYMER DISPERSIONS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF BASF SE (DE) 2019-05-08 EP disclosed
US-4751277-A OIL-RESISTANT RUBBER JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1988-06-14 US disclosed
US-4606952-A MULTILAYER-FLUOROPOLYMER WITH ACRYLONITRILE-BUTADIENE COPOLYMER TOYODA GOSEI CO., LTD. (JP) 1986-08-19 US disclosed
US-4288357-A PARTIALLY HYDROLYZED SILICON COMPOUND AND A POLYOL SUMITOMO CHEMICAL CO. LTD. (JP) 1981-09-08 US disclosed
US-4271230-A HEAT AND AGING RESISTANCE SUMITOMO NAUGATUCK CO., LTD. (JP) 1981-06-02 US disclosed
US-4190699-A WITH PARTIALLY HYDROLYZED SILICON COMPOUNDS AND ACRYLIC COPOLYMER FOLLOWED BY CURING SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1980-02-26 US disclosed
US-4091165-A COATING OF A POLYMER OF AMINOALKYL ACRYLATE, ALKYL ACRYLATE AND VINYL MONOMER TREATED WITH HALOACETIC ACID SALT MITSUBISHI PETROCHEMICAL CO., LTD. (JA) 1978-05-23 US disclosed
US-4082894-A COATING WITH PRIMER POLYMER, DRYING, CURING MELAMINE-TYPE RESIN COATING NIPPON SHEET GLASS CO., LTD. (JA) 1978-04-04 US disclosed