Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 7/20 | 0.46 |
| ▸ | DRD2 | P14416 | 4/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GHSR | Q92847 | 1/20 | 0.42 |
| ▸ | UBE2M | P61081 | 1/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018943 | 0.89 | DRD3 (0.50) | DRD3DRD2DRD4HTR1DHTR1B | |
| SCHEMBL30705737 | 0.89 | DRD3 (0.50) | DRD3DRD2DRD4HTR1DHTR1B | |
| Cyclopropane Carboxylic Acid SCHEMBL17822673 | 0.89 | TAS2R14 (0.48) | DRD3DRD2DRD4HTR1DHTR1B | |
| SCHEMBL8688537 | 0.88 | DRD3 (0.50) | DRD3DRD2DRD4HTR1DHTR1B | |
| SCHEMBL30705735 | 0.85 | DRD3 (0.46) | DRD3DRD2DRD4HTR1DHTR1B | |
| SCHEMBL8691516 | 0.85 | DRD3 (0.46) | DRD3DRD2DRD4HTR1DHTR1B | |
| SCHEMBL30705739 | 0.81 | DRD3 (0.48) | DRD3DRD2DRD4HTR1DHTR1B | |
| SCHEMBL8689579 | 0.81 | DRD3 (0.48) | DRD3DRD2DRD4HTR1DHTR1B | |
| Cyclopropane Carboxylic Acid SCHEMBL19989732 | 0.78 | DRD3 (0.48) | DRD3DRD2DRD4HTR1DHTR1B | |
| SCHEMBL7451185 | 0.77 | DRD3 (0.55) | DRD3DRD2DRD4HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708018-A | 2-aminoindans as selective dopamine D3 ligands | PHARMACIA & UPJOHN COMPANY (US) | 1998-01-13 | — | — | US | disclosed |