Cyclopropane Carboxylic Acid

Cyclopropane Carboxylic Acid

SCHEMBL17822673

CCCN(Cc1ccccc1)C1Cc2ccc(NC(C)=O)cc2C1.O=C(O)C1CC1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TAS2R14 Q9NYV8 3/20 0.48
DRD3 P35462 8/20 0.45
DRD2 P14416 6/20 0.43
DRD4 P21917 1/20 0.42
HTR1D P28221 1/20 0.42
HTR1B P28222 1/20 0.42
UBE2M P61081 1/20 0.40
DCUN1D1 Q96GG9 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8688537 0.94 DRD3 (0.50) DRD3DRD2DRD4HTR1DHTR1B
SCHEMBL8689595 0.89 DRD3 (0.46) DRD3DRD2DRD4HTR1DHTR1B
SCHEMBL9018943 0.87 DRD3 (0.50) DRD3DRD2DRD4HTR1DHTR1B
SCHEMBL30705737 0.87 DRD3 (0.50) DRD3DRD2DRD4HTR1DHTR1B
SCHEMBL8691516 0.83 DRD3 (0.46) DRD3DRD2DRD4HTR1DHTR1B
SCHEMBL30705735 0.83 DRD3 (0.46) DRD3DRD2DRD4HTR1DHTR1B
Cyclopropane Carboxylic Acid SCHEMBL19989732 0.81 DRD3 (0.48) DRD3DRD2DRD4HTR1DHTR1B
SCHEMBL8689579 0.78 DRD3 (0.48) DRD3DRD2DRD4HTR1DHTR1B
SCHEMBL30705739 0.78 DRD3 (0.48) DRD3DRD2DRD4HTR1DHTR1B
SCHEMBL10447705 0.77 DRD3 (0.60) DRD3DRD2DRD4HTR1DHTR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024062395-A1 USE OF 5-METHOXY-2-AMINOINDAN (\"MEAI\") IN METHODS FOR TREATING METABOLIC SYNDROME Clearmind Medicine Inc. (IL) 2024-03-28 WO disclosed
US-11528924-B2 Alcoholic beverage substitutes Clearmind Medicine, Inc. (CA) 2022-12-20 US disclosed
US-20210330608-A1 BINGE BEHAVIOR REGULATORS CLEARMIND LABS CORP. (CA) 2021-10-28 US disclosed
US-20210330609-A1 BINGE BEHAVIOR REGULATORS CLEARMIND LABS CORP. (CA) 2021-10-28 US disclosed
EP-3705469-A1 BINGE BEHAVIOR REGULATORS GOLAN, Ezekiel (CA) 2020-09-09 EP disclosed
EP-3230255-B1 BINGE BEHAVIOR REGULATORS GOLAN EZEKIEL (CA) 2020-03-18 EP disclosed
EP-3230256-B1 ALCOHOLIC BEVERAGE SUBSTITUTES GOLAN EZEKIEL (CA) 2019-11-13 EP disclosed
US-20170360067-A1 ALCOHOLIC BEVERAGE SUBSTITUTES CLEARMIND LABS CORP. (CA) 2017-12-21 US disclosed
EP-3230255-A1 BINGE BEHAVIOR REGULATORS Golan, Ezekiel (CA) 2017-10-18 EP disclosed
EP-3230256-A1 ALCOHOLIC BEVERAGE SUBSTITUTES Golan, Ezekiel (CA) 2017-10-18 EP disclosed
WO-2016092546-A1 BINGE BEHAVIOR REGULATORS GOLAN EZEKIEL (IL) 2016-06-16 WO disclosed
WO-2016092547-A1 ALCOHOLIC BEVERAGE SUBSTITUTES GOLAN EZEKIEL (IL) 2016-06-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210330609-A1 BINGE BEHAVIOR REGULATORS GABRB3, GABRB2, GABRB1 TAS2R14 337/4885DRD3 131/4885DRD2 62/4885
US-11528924-B2 Alcoholic beverage substitutes ADH1A, ADH5, ADH1C TAS2R14 288/4885DRD3 431/4885DRD2 456/4885
US-20210330608-A1 BINGE BEHAVIOR REGULATORS GABRB3, GABRB2, GABRB1 TAS2R14 337/4885DRD3 131/4885DRD2 62/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.