Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ACR | P10323 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8690167 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MAPTLMNAHPGDNPSR1 | |
| SCHEMBL9522428 | 0.76 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNAHPGDNPSR1 | |
| SCHEMBL9522459 | 0.76 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNAHPGDNPSR1 | |
| SCHEMBL9522255 | 0.76 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNAHPGDNPSR1 | |
| SCHEMBL10462493 | 0.76 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNAHPGDNPSR1 | |
| SCHEMBL9523579 | 0.76 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNAHPGDNPSR1 | |
| SCHEMBL9041851 | 0.76 | MAPT (0.54) | ALDH1A1MAPTLMNAHPGDNPSR1 | |
| SCHEMBL406428 | 0.72 | TSHR (0.74) | ALDH1A1MAPTLMNAHPGDKDM4E | |
| SCHEMBL11493783 | 0.72 | MAPK8 (0.53) | ALDH1A1MAPTLMNAHPGDNPSR1 | |
| SCHEMBL11861209 | 0.72 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNAHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760032-A | GASTROINTESTINAL DISORDERS AND NERVOUS SYSTEM DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-06-02 | — | — | US | disclosed |
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |