Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | GRM6 | O15303 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | ACR | P10323 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9654311 | 0.83 | RAB9A (0.47) | ALDH1A1MAPTHPGDGAARAB9A | |
| SCHEMBL9038479 | 0.81 | ALDH1A1 (0.48) | ALDH1A1MAPTHPGDGAAHSD17B10 | |
| SCHEMBL9669232 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MAPTGAAHSD17B10ALOX15 | |
| SCHEMBL8692246 | 0.80 | RECQL (0.53) | ALDH1A1HPGDGAALMNAKDM4E | |
| SCHEMBL12963136 | 0.79 | GAA (0.69) | ALDH1A1MAPTHPGDGAAHSD17B10 | |
| SCHEMBL8689607 | 0.79 | ALDH1A1 (0.51) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA | |
| SCHEMBL8691598 | 0.79 | LMNA (0.50) | ALDH1A1MAPTHPGDGAAHSD17B10 | |
| SCHEMBL9039352 | 0.78 | LMNA (0.67) | ALDH1A1MAPTGAAHSD17B10ALOX15 | |
| SCHEMBL9651407 | 0.77 | TAS1R3 (0.58) | — | |
| SCHEMBL13110240 | 0.77 | ALDH1A1 (0.42) | ALDH1A1MAPTHPGDGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760032-A | GASTROINTESTINAL DISORDERS AND NERVOUS SYSTEM DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-06-02 | — | — | US | disclosed |
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |