Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | TACR2 | P21452 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SHBG | P04278 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1586370 | 0.95 | SLC7A5 (0.49) | SLC7A5TRPV1ESR1ADRA2ASLC6A2 | |
| SCHEMBL1586369 | 0.95 | SLC7A5 (0.49) | SLC7A5TRPV1ESR1ADRA2ASLC6A2 | |
| SCHEMBL23700720 | 0.87 | SLC7A5 (0.52) | SLC7A5ESR1ADRA2ASLC6A2KDM4E | |
| SCHEMBL27734517 | 0.81 | GRIK1 (0.44) | SPHK1 | |
| SCHEMBL27734516 | 0.81 | GRIK1 (0.44) | SPHK1 | |
| SCHEMBL27734653 | 0.79 | PPARG (0.51) | SLC6A4IGF1RALOX15CYP2C19HTR3A | |
| SCHEMBL18522449 | 0.79 | GRIK1 (0.43) | LMNATAAR1 | |
| SCHEMBL27734651 | 0.79 | PPARG (0.51) | SLC6A4IGF1RALOX15CYP2C19HTR3A | |
| SCHEMBL27734646 | 0.79 | GRIK1 (0.43) | LMNATAAR1 | |
| SCHEMBL29032086 | 0.79 | GRIK1 (0.61) | SLC7A5SLC6A3LMNAPTGS1HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756507-A | TREATING SEX HORMONE RELATED DISORDERS | MERCK & CO., INC. (US) | 1998-05-26 | — | — | US | claimed |
| US-5756507-A | TREATING SEX HORMONE RELATED DISORDERS | MERCK & CO., INC. (US) | 1998-05-26 | — | — | US | disclosed |