Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 2/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1586370 | 0.89 | SLC7A5 (0.49) | SLC7A5CA2ESR1ESR2TAAR1 | |
| SCHEMBL1586369 | 0.89 | SLC7A5 (0.49) | SLC7A5CA2ESR1ESR2TAAR1 | |
| SCHEMBL8689779 | 0.87 | SLC7A5 (0.47) | SLC7A5CA2ESR1ESR2TAAR1 | |
| SCHEMBL1768639 | 0.85 | SLC7A5 (0.67) | SLC7A5CA2ESR1ESR2TAAR1 | |
| SCHEMBL1666620 | 0.85 | SLC7A5 (0.67) | SLC7A5CA2ESR1ESR2TAAR1 | |
| SCHEMBL9394667 | 0.85 | SLC7A5 (0.67) | SLC7A5CA2ESR1ESR2TAAR1 | |
| Bromide SCHEMBL29399073 | 0.83 | SLC7A5 (0.65) | SLC7A5ESR1ESR2TAAR1SLC6A2 | |
| SCHEMBL29714755 | 0.83 | SLC7A5 (0.55) | SLC7A5ESR1ESR2TAAR1SLC6A2 | |
| SCHEMBL23762403 | 0.83 | SLC7A5 (0.55) | SLC7A5ESR1ESR2TAAR1SLC6A2 | |
| Bromide SCHEMBL919214 | 0.83 | SLC7A5 (0.65) | SLC7A5ESR1ESR2TAAR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242479-A1 | ALKYLAMINE-SUBSTITUTED PERTHIOCARBAMATES AS DUAL PRECURSORS TO HYDROPERSULFIDE AND CARBONYL SULFIDE | THE JOHNS HOPKINS UNIVERSTY | 2023-08-03 | — | — | US | disclosed |
| US-11584712-B2 | Alkylamine-substituted perthiocarbamates as dual precursors to hydropersulfide and carbonyl sulfide | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-02-21 | — | — | US | disclosed |
| US-20210238134-A1 | ALKYLAMINE-SUBSTITUTED PERTHIOCARBAMATES AS DUAL PRECURSORS TO HYDROPERSULFIDE AND CARBONYL SULFIDE | NATIONAL SCIENCE FOUNDATION | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238134-A1 | ALKYLAMINE-SUBSTITUTED PERTHIOCARBAMATES AS DUAL PRECURSORS TO HYDROPERSULFIDE AND CARBONYL SULFIDE | CTH, DOHH, HAGH | SLC7A5 293/4885CA2 780/4885ESR1 4223/4885 |
| US-20230242479-A1 | ALKYLAMINE-SUBSTITUTED PERTHIOCARBAMATES AS DUAL PRECURSORS TO HYDROPERSULFIDE AND CARBONYL SULFIDE | CTH, DOHH, HAGH | SLC7A5 293/4885CA2 780/4885ESR1 4223/4885 |
| US-11584712-B2 | Alkylamine-substituted perthiocarbamates as dual precursors to hydropersulfide and carbonyl sulfide | CTH, DOHH, HAGH | SLC7A5 293/4885CA2 780/4885ESR1 4223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.