Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CCKAR | P32238 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8689620 | 0.92 | MEN1 (0.41) | KMT2AMEN1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL8694118 | 0.91 | SMN1; SMN2 (0.33) | KMT2AMEN1ALDH1A1CYP1A2POLB | |
| SCHEMBL8689114 | 0.91 | MEN1 (0.39) | KMT2AMEN1ALDH1A1CYP1A2POLB | |
| SCHEMBL8689483 | 0.83 | OPRK1 (0.35) | KMT2AMEN1ALDH1A1CYP1A2POLB | |
| SCHEMBL8694005 | 0.83 | MEN1 (0.39) | KMT2AMEN1ALDH1A1CYP1A2POLB | |
| SCHEMBL8689743 | 0.83 | ALDH1A1 (0.40) | KMT2AMEN1ALDH1A1CYP1A2POLB | |
| SCHEMBL8694534 | 0.83 | OPRK1 (0.35) | KMT2AMEN1ALDH1A1CCKARTSHR | |
| SCHEMBL8689076 | 0.82 | MEN1 (0.38) | KMT2AMEN1ALDH1A1CYP1A2POLB | |
| SCHEMBL8689308 | 0.82 | MEN1 (0.40) | KMT2AMEN1ALDH1A1CYP1A2POLB | |
| SCHEMBL8689799 | 0.82 | MEN1 (0.37) | KMT2AMEN1ALDH1A1CYP1A2CCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760032-A | GASTROINTESTINAL DISORDERS AND NERVOUS SYSTEM DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-06-02 | — | — | US | disclosed |