Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HK1 | P19367 | 1/20 | 0.46 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.46 |
| ▸ | F10 | P00742 | 4/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8689468 | 0.84 | ALDH1A1 (0.55) | MEN1KMT2ANPSR1SMN1; SMN2LMNA | |
| SCHEMBL18733289 | 0.84 | F10 (0.52) | MEN1KMT2AMAPTF10LTB4R | |
| SCHEMBL8694830 | 0.83 | MEN1 (0.69) | MEN1KMT2ASMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL830229 | 0.83 | KDM4E (0.49) | MEN1KMT2ANPSR1SMN1; SMN2LMNA | |
| SCHEMBL6741019 | 0.81 | MEN1 (0.47) | MEN1KMT2ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL18733230 | 0.80 | MAOA (0.51) | MEN1KMT2AMAPTF10LTB4R | |
| SCHEMBL18733434 | 0.78 | MEN1 (0.53) | MEN1KMT2ANPSR1SMN1; SMN2LMNA | |
| SCHEMBL7688134 | 0.78 | F10 (0.46) | MEN1KMT2AKDM4EALDH1A1NOD2 | |
| SCHEMBL7684727 | 0.78 | F10 (0.46) | MEN1KMT2ALMNAL3MBTL1KDM4E | |
| SCHEMBL832448 | 0.78 | F10 (0.61) | MEN1KMT2ANPSR1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760032-A | GASTROINTESTINAL DISORDERS AND NERVOUS SYSTEM DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-06-02 | — | — | US | disclosed |
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |