Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 11/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 11/20 | 0.33 |
| ▸ | PDE4A | P27815 | 5/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | RARG | P13631 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8690586 | 0.82 | GAA (0.31) | PDE4BPDE4CPDE4APDE4DRECQL | |
| SCHEMBL8688274 | 0.80 | PDE4B (0.41) | PDE4BPDE4CPDE4APDE4DTNF | |
| SCHEMBL8690107 | 0.79 | PDE4B (0.33) | PDE4BPDE4CPDE4APDE4DRECQL | |
| SCHEMBL8690592 | 0.79 | RECQL (0.33) | PDE4BPDE4CPDE4APDE4DRECQL | |
| SCHEMBL8690105 | 0.79 | PDE4A (0.32) | PDE4BPDE4CPDE4APDE4DRECQL | |
| SCHEMBL8690589 | 0.77 | PDE4A (0.31) | PDE4BPDE4CPDE4APDE4DRECQL | |
| SCHEMBL8688141 | 0.64 | PDE4B (0.40) | PDE4BPDE4CPDE4APDE4DTNF | |
| SCHEMBL8688151 | 0.64 | TNF (0.42) | PDE4BPDE4CPDE4APDE4DRECQL | |
| SCHEMBL8688278 | 0.64 | TNF (0.43) | PDE4BPDE4CPDE4APDE4DTNF | |
| SCHEMBL8128979 | 0.63 | RARG (0.39) | RARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710147-A | ANTIBIOTICS | ROUSSEL UCLAF (FR) | 1998-01-20 | — | — | US | disclosed |