Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8690589 | 0.87 | PDE4A (0.31) | PDE4APDE4BPDE4CPDE4DRARG | |
| SCHEMBL8690107 | 0.83 | PDE4B (0.33) | PDE4APDE4BPDE4CPDE4DRARG | |
| SCHEMBL8690586 | 0.83 | GAA (0.31) | PDE4APDE4BPDE4CPDE4DRARG | |
| SCHEMBL8690592 | 0.81 | RECQL (0.33) | PDE4APDE4BPDE4CPDE4DRARG | |
| SCHEMBL8690102 | 0.79 | PDE4B (0.33) | PDE4APDE4BPDE4CPDE4DRARG | |
| SCHEMBL8688277 | 0.79 | PDE4B (0.41) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8688145 | 0.68 | PDE4B (0.40) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8688278 | 0.66 | TNF (0.43) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8688151 | 0.64 | TNF (0.42) | PDE4APDE4BPDE4CPDE4DRECQL | |
| SCHEMBL8688141 | 0.64 | PDE4B (0.40) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710147-A | ANTIBIOTICS | ROUSSEL UCLAF (FR) | 1998-01-20 | — | — | US | disclosed |