Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.62 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.62 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8650015 | 0.89 | ITGB3 (0.73) | ITGB3ITGA2BACEF2PLG | |
| SCHEMBL7285135 | 0.87 | ITGB3 (0.82) | ITGB3ITGA2BCYP51A1F2PLG | |
| SCHEMBL8689992 | 0.82 | ITGB3 (0.57) | ITGB3ITGA2BF10F2 | |
| SCHEMBL7302621 | 0.81 | ITGB3 (0.53) | ITGB3ITGA2BCYP51A1F10F2 | |
| SCHEMBL7302642 | 0.80 | CYP51A1 (0.54) | ITGB3ITGA2BCYP51A1F10F2 | |
| SCHEMBL6099449 | 0.79 | ITGB3 (0.75) | ITGB3ITGA2BCYP51A1F2PLG | |
| SCHEMBL4425018 | 0.79 | ITGB3 (0.75) | ITGB3ITGA2BCYP51A1F2PLG | |
| SCHEMBL7293550 | 0.78 | ITGB3 (0.68) | ITGB3ITGA2BCYP51A1F10F2 | |
| SCHEMBL7274759 | 0.78 | ITGB3 (0.68) | ITGB3ITGA2BCYP51A1F10F2 | |
| SCHEMBL8881333 | 0.77 | ITGB3 (0.65) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5747522-A | ANTICOAGULANTS; ANTIINFLAMMATORY AGENTS; ANTITUMOR AGENTS | HOFFMAN-LA ROCHE INC. (US) | 1998-05-05 | — | — | US | disclosed |
| US-5670515-A | TREATMENT OF THROMBOSIS, STROKE, CARDIAC INFARCT, INFLAMMATION, AND ARTERIOSCLEROSIS; ANTITUMOR AGENTS, WOUND HEALING AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1997-09-23 | — | — | US | disclosed |