Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8690408 | 0.98 | NAAA (0.50) | NAAAHCAR2EPHX1ATMTSHR | |
| SCHEMBL450231 | 0.94 | ATM (0.50) | NAAAHCAR2EPHX1ATMTSHR | |
| SCHEMBL448627 | 0.86 | NAAA (0.48) | NAAAHCAR2EPHX1ATMTSHR | |
| SCHEMBL451518 | 0.86 | HCAR2 (0.41) | HCAR2ATMTSHRALDH1A1HPGD | |
| SCHEMBL449591 | 0.85 | NAAA (0.52) | NAAAHCAR2EPHX1ATMTSHR | |
| SCHEMBL450736 | 0.80 | NAAA (0.50) | NAAAHCAR2EPHX1ATMTSHR | |
| SCHEMBL1115645 | 0.80 | NAAA (0.50) | NAAAHCAR2EPHX1ATMTSHR | |
| SCHEMBL451520 | 0.80 | ATM (0.52) | NAAAHCAR2EPHX1ATMTSHR | |
| SCHEMBL449195 | 0.79 | ALDH1A1 (0.52) | HCAR2ALDH1A1FAAHNPSR1 | |
| SCHEMBL37366 | 0.79 | NAAA (0.62) | NAAAHCAR2EPHX1ATMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827863-A | Pyrazole derivatives as angiotensin II antagonists | J. URIACH & CIA, S.A. (ES) | 1998-10-27 | — | — | US | disclosed |
| EP-0721454-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA. S.A. (ES) | 1996-07-17 | — | — | EP | disclosed |
| WO-1996004273-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA, S.A. (ES) | 1996-02-15 | — | — | WO | disclosed |