Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.83 |
| ▸ | MEN1 | O00255 | 2/20 | 0.83 |
| ▸ | ATM | Q13315 | 1/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.72 |
| ▸ | TBXAS1 | P24557 | 8/20 | 0.71 |
| ▸ | NOS1 | P29475 | 1/20 | 0.67 |
| ▸ | QPCT | Q16769 | 1/20 | 0.66 |
| ▸ | LTA4H | P09960 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9786362 | 0.89 | MEN1 (0.86) | KMT2AMEN1ATMKDM4ENOS1 | |
| SCHEMBL13246359 | 0.87 | QPCT (0.85) | KMT2AMEN1ATMALDH1A1KDM4E | |
| SCHEMBL8685444 | 0.84 | ALDH1A1 (0.78) | KMT2AALDH1A1KDM4EMAPK1TBXAS1 | |
| SCHEMBL76839 | 0.84 | KDM4E (0.72) | KMT2AMEN1ALDH1A1KDM4EMAPK1 | |
| SCHEMBL10785887 | 0.84 | KDM4E (0.72) | KMT2AMEN1ALDH1A1KDM4EMAPK1 | |
| SCHEMBL305632 | 0.84 | ALDH1A1 (0.72) | KMT2AMEN1ALDH1A1KDM4EMAPK1 | |
| SCHEMBL8684965 | 0.84 | MAPK1 (1.00) | KMT2AMEN1ALDH1A1KDM4EMAPK1 | |
| SCHEMBL10370478 | 0.83 | TBXAS1 (1.00) | KMT2AMEN1ALDH1A1KDM4EMAPK1 | |
| SCHEMBL13761576 | 0.83 | MEN1 (0.86) | KMT2AMEN1ATMALDH1A1KDM4E | |
| SCHEMBL1369627 | 0.83 | KDM4E (0.70) | KMT2AMEN1ALDH1A1KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708171-A | HISTAMINE H3-RECEPTOR ANTAGONIST | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1998-01-13 | — | — | US | claimed |
| US-5708171-A | HISTAMINE H3-RECEPTOR ANTAGONIST | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1998-01-13 | — | — | US | disclosed |