Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.58 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 5/20 | 0.54 |
| ▸ | ACHE | P22303 | 5/20 | 0.54 |
| ▸ | LTA4H | P09960 | 5/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 3/20 | 0.53 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.52 |
| ▸ | CKS1B | P61024 | 1/20 | 0.52 |
| ▸ | SKP1 | P63208 | 1/20 | 0.52 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8693002 | 0.88 | HTR7 (0.60) | HTR7TMEM97SIGMAR1LTA4HKCNA5 | |
| SCHEMBL8692602 | 0.84 | TMEM97 (0.63) | HTR7TMEM97SIGMAR1LTA4HKDM4E | |
| Hydrochloric Acid SCHEMBL8691470 | 0.83 | TMEM97 (0.61) | HTR7TMEM97SIGMAR1LTA4HKDM4E | |
| SCHEMBL8694210 | 0.81 | TMEM97 (0.60) | HTR7TMEM97SIGMAR1LTA4HKDM4E | |
| SCHEMBL23366712 | 0.81 | TMEM97 (0.66) | HTR7TMEM97SIGMAR1LTA4H | |
| Hydrochloric Acid SCHEMBL8693232 | 0.81 | TMEM97 (0.59) | HTR7TMEM97SIGMAR1LTA4HKDM4E | |
| SCHEMBL13499317 | 0.80 | HTR7 (0.53) | HTR7TMEM97SIGMAR1FAAHACHE | |
| SCHEMBL17517685 | 0.79 | HDAC3 (0.68) | FAAHACHEBCHE | |
| SCHEMBL8694338 | 0.78 | TMEM97 (0.69) | TMEM97SIGMAR1LTA4HKDM4E | |
| SCHEMBL12642580 | 0.77 | LTA4H (0.52) | HTR7LTA4HKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760035-A | PIPERIDINE COMPOUNDS SUBSTITUTED WITH AN AMINOALKYL GROUP AND AN ARYLOXYALKYL GROUP, ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, IMMUNOSUPPRESSANTS | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-06-02 | — | — | US | disclosed |
| EP-0720602-B1 | 4-ALKYLAMINO-1-PHENOXYALKYL PIPERIDINES AS ANTIINFLAMMATORY, ANTIALLERGIC AND IMMUNOMODULATING AGENTS | KNOLL AG (DE) | 1997-07-09 | — | — | EP | disclosed |
| EP-0720602-A1 | 4-ALKYLAMINO-1-PHENOXYALKYL PIPERIDINES AS ANTIINFLAMMATORY, ANTIALLERGIC AND IMMUNOMODULATING AGENTS | KNOLL AG (DE) | 1996-07-10 | — | — | EP | disclosed |
| WO-1995008535-A1 | 4-ALKYLAMINO-1-PHENOXYALKYL PIPERIDINES AS ANTIINFLAMMATORY, ANTIALLERGIC AND IMMUNOMODULATING AGENTS | KNOLL AG (DE) | 1995-03-30 | — | — | WO | disclosed |