Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8691041 | 1.00 | FFAR1 (0.48) | FFAR1LTA4HEPHX2MMP12FFAR4 | |
| SCHEMBL8690009 | 1.00 | FFAR1 (0.48) | FFAR1LTA4HEPHX2MMP12FFAR4 | |
| SCHEMBL8692695 | 0.88 | NPC1 (0.47) | FFAR1BCL2 | |
| SCHEMBL8690348 | 0.88 | NPC1 (0.47) | FFAR1BCL2 | |
| SCHEMBL8690103 | 0.88 | NPC1 (0.47) | FFAR1BCL2 | |
| SCHEMBL8502674 | 0.86 | LTA4H (0.54) | FFAR1LTA4HEPHX2MMP12FFAR4 | |
| SCHEMBL8688113 | 0.84 | ALDH1A1 (0.40) | — | |
| SCHEMBL8692922 | 0.84 | ALDH1A1 (0.40) | — | |
| SCHEMBL8505443 | 0.84 | ALDH1A1 (0.40) | — | |
| SCHEMBL8504961 | 0.76 | LTA4H (0.46) | FFAR1LTA4HEPHX2MMP12FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789434-A | ACID, ESTER OR AMIDE DERIVATIVES AS ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS AND REDUCTION OF CARTILAGE DETERIORATION | BAYER CORPORATION (US) | 1998-08-04 | — | — | US | disclosed |