Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.44 |
| ▸ | CYP24A1 | Q07973 | 7/20 | 0.44 |
| ▸ | ICMT | O60725 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 5/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29935620 | 0.82 | ALDH1A1 (0.43) | CYP24A1NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL29955958 | 0.82 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL1253456 | 0.82 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL29128741 | 0.81 | ALDH1A1 (0.63) | CDC25AICMTNPC1ALDH1A1MAPT | |
| SCHEMBL8702147 | 0.81 | ALDH1A1 (0.63) | CDC25AICMTNPC1ALDH1A1MAPT | |
| SCHEMBL29071735 | 0.81 | ALDH1A1 (0.63) | CDC25AICMTNPC1ALDH1A1MAPT | |
| SCHEMBL9317815 | 0.81 | ALDH1A1 (0.63) | CDC25AICMTNPC1ALDH1A1MAPT | |
| SCHEMBL29277397 | 0.81 | ALDH1A1 (0.63) | CDC25AICMTNPC1ALDH1A1MAPT | |
| SCHEMBL29277420 | 0.81 | ALDH1A1 (0.63) | CDC25AICMTNPC1ALDH1A1MAPT | |
| SCHEMBL11903655 | 0.79 | ALDH1A1 (0.64) | CDC25AICMTNPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811439-A | ANTIDIABETIC AGENTS; SIDE EFFECT REDUCTION; ANTILEPEMIC AGENTS | SENGA PHARMACEUTICAL LABORATORY INC. (JP) | 1998-09-22 | — | — | US | disclosed |
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |