Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | CYP24A1 | Q07973 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8686722 | 0.87 | ICMT (0.42) | ALDH1A1IMPDH2POLBAPPTDP1 | |
| SCHEMBL8685437 | 0.82 | POLB (0.55) | ALDH1A1IMPDH2POLBTDP1L3MBTL1 | |
| SCHEMBL15519691 | 0.81 | HTR2C (0.41) | HTR2CALDH1A1IMPDH2POLBAPP | |
| SCHEMBL29935620 | 0.81 | ALDH1A1 (0.43) | HTR2CALDH1A1IMPDH2POLBAPP | |
| SCHEMBL29955958 | 0.77 | ALDH1A1 (0.43) | ALDH1A1IMPDH2POLBAPPTDP1 | |
| SCHEMBL1253456 | 0.77 | ALDH1A1 (0.43) | ALDH1A1IMPDH2POLBAPPTDP1 | |
| SCHEMBL2034817 | 0.77 | POLB (0.49) | ALDH1A1IMPDH2POLBCYP24A1TDP1 | |
| SCHEMBL8811841 | 0.77 | PARP1 (0.49) | ALDH1A1TDP1MAPTHTT | |
| SCHEMBL8811840 | 0.77 | PARP1 (0.49) | ALDH1A1TDP1MAPTHTT | |
| SCHEMBL8811843 | 0.77 | PARP1 (0.37) | HTR2CALDH1A1POLBCYP24A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811439-A | ANTIDIABETIC AGENTS; SIDE EFFECT REDUCTION; ANTILEPEMIC AGENTS | SENGA PHARMACEUTICAL LABORATORY INC. (JP) | 1998-09-22 | — | — | US | disclosed |
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |