Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 10/20 | 0.50 |
| ▸ | DRD2 | P14416 | 5/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8693731 | 0.88 | LTA4H (0.53) | LTA4HDRD3DRD2HRH3MEN1 | |
| SCHEMBL8696174 | 0.88 | LTA4H (0.50) | LTA4HHRH3MEN1KMT2AKCNA5 | |
| Hydrochloric Acid SCHEMBL8690258 | 0.87 | LTA4H (0.49) | LTA4HMEN1KMT2AKCNA5 | |
| SCHEMBL8690263 | 0.82 | DRD2 (0.46) | LTA4HDRD3DRD2MEN1KMT2A | |
| SCHEMBL9027139 | 0.75 | LTA4H (0.50) | LTA4HDRD3DRD2HRH3 | |
| SCHEMBL15257179 | 0.74 | LTA4H (0.82) | LTA4HDRD3HRH3POLBMAPT | |
| SCHEMBL14970684 | 0.74 | LTA4H (0.82) | LTA4HDRD3HRH3POLBMAPT | |
| SCHEMBL8689825 | 0.73 | LTA4H (0.55) | LTA4HDRD3DRD2HRH3KMT2A | |
| SCHEMBL13150791 | 0.72 | DRD3 (0.72) | LTA4HDRD3DRD2KCNA5 | |
| Hydrochloric Acid SCHEMBL14966283 | 0.72 | LTA4H (0.79) | LTA4HDRD3HRH3POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760035-A | PIPERIDINE COMPOUNDS SUBSTITUTED WITH AN AMINOALKYL GROUP AND AN ARYLOXYALKYL GROUP, ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, IMMUNOSUPPRESSANTS | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-06-02 | — | — | US | disclosed |
| EP-0720602-B1 | 4-ALKYLAMINO-1-PHENOXYALKYL PIPERIDINES AS ANTIINFLAMMATORY, ANTIALLERGIC AND IMMUNOMODULATING AGENTS | KNOLL AG (DE) | 1997-07-09 | — | — | EP | disclosed |
| EP-0720602-A1 | 4-ALKYLAMINO-1-PHENOXYALKYL PIPERIDINES AS ANTIINFLAMMATORY, ANTIALLERGIC AND IMMUNOMODULATING AGENTS | KNOLL AG (DE) | 1996-07-10 | — | — | EP | disclosed |
| WO-1995008535-A1 | 4-ALKYLAMINO-1-PHENOXYALKYL PIPERIDINES AS ANTIINFLAMMATORY, ANTIALLERGIC AND IMMUNOMODULATING AGENTS | KNOLL AG (DE) | 1995-03-30 | — | — | WO | disclosed |