Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.47 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7445037 | 0.87 | CHRNB2 (0.58) | KCNH2CYP19A1CHRNB2CHRNA4LMNA | |
| SCHEMBL11140919 | 0.86 | HTT (0.55) | KCNH2ATML3MBTL1CYP19A1ALK | |
| SCHEMBL14204587 | 0.86 | KCNH2 (0.52) | KCNH2ATML3MBTL1CYP19A1ALK | |
| SCHEMBL4015134 | 0.85 | MAPT (0.53) | KCNH2ATML3MBTL1CYP19A1LMNA | |
| SCHEMBL21852317 | 0.85 | KCNH2 (0.51) | KCNH2ATML3MBTL1CYP19A1ALK | |
| SCHEMBL3859288 | 0.83 | KCNH2 (0.52) | KCNH2ATML3MBTL1CYP19A1ALK | |
| SCHEMBL4010453 | 0.82 | S1PR4 (0.57) | KCNH2ATML3MBTL1CYP19A1ALK | |
| SCHEMBL3861829 | 0.82 | ALDH1A1 (0.53) | KCNH2ATML3MBTL1CYP19A1ALK | |
| SCHEMBL28514305 | 0.82 | ATM (0.52) | KCNH2ATML3MBTL1CYP19A1ALK | |
| SCHEMBL3858494 | 0.82 | MAPT (0.63) | KCNH2ATML3MBTL1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5801170-A | Heterocyclic biphenylylamides useful as 5HT1D antagonists | SMITHKLINE BEECHAM PLC (GB) | 1998-09-01 | — | — | US | disclosed |