Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITPR3 | Q14573 | 9/20 | 0.53 |
| ▸ | ITPR2 | Q14571 | 5/20 | 0.53 |
| ▸ | ITPR1 | Q14643 | 5/20 | 0.53 |
| ▸ | INPP5A | Q14642 | 3/20 | 0.53 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.53 |
| ▸ | AKT1 | P31749 | 1/20 | 0.53 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8691271 | 1.00 | ITPR3 (0.53) | ITPR3ITPR2ITPR1INPP5AINPPL1 | |
| SCHEMBL17830376 | 0.89 | SMPD1 (0.47) | ITPR3ITPR2ITPR1INPP5AINPPL1 | |
| SCHEMBL16869500 | 0.82 | SMPD1 (0.38) | ITPR3ITPR2ITPR1INPP5AINPPL1 | |
| SCHEMBL1331808 | 0.76 | ITPR3 (0.89) | ITPR3ITPR2ITPR1INPP5AINPPL1 | |
| SCHEMBL29635055 | 0.76 | ITPR3 (0.89) | ITPR3ITPR2ITPR1INPP5AINPPL1 | |
| SCHEMBL9439385 | 0.76 | ITPR3 (0.89) | ITPR3ITPR2ITPR1INPP5AINPPL1 | |
| SCHEMBL9439624 | 0.76 | ITPR3 (0.89) | ITPR3ITPR2ITPR1INPP5AINPPL1 | |
| SCHEMBL8441712 | 0.76 | ITPR3 (0.89) | ITPR3ITPR2ITPR1INPP5AINPPL1 | |
| Ionositol (1,3,4,5,6) P5 SCHEMBL2710469 | 0.73 | ITPR3 (0.94) | ITPR3ITPR2ITPR1INPP5AINPPL1 | |
| Ionositol (1,3,4,5,6) P5 SCHEMBL5159171 | 0.73 | ITPR3 (0.94) | ITPR3ITPR2ITPR1INPP5AINPPL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756774-A | Synthesis of myo-inositol phosphates | ELAN PHARMACEUTICALS, INC. | 1998-05-26 | — | — | US | claimed |
| US-5756774-A | Synthesis of myo-inositol phosphates | ELAN PHARMACEUTICALS, INC. | 1998-05-26 | — | — | US | disclosed |