SCHEMBL17830376

SCHEMBL17830376

CC1(C)O[C@H]2[C@H]3OC(C)(C)O[C@H]3[C@@H](O)[C@@H](OP(=O)(O)O)[C@H]2O1

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SMPD1 P17405 1/20 0.47
ITPR3 Q14573 10/20 0.45
ITPR2 Q14571 5/20 0.45
ITPR1 Q14643 5/20 0.45
INPP5A Q14642 4/20 0.44
INPPL1 O15357 1/20 0.44
AKT1 P31749 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8691271 0.89 ITPR3 (0.53) SMPD1ITPR3ITPR2ITPR1INPP5A
SCHEMBL8690883 0.89 ITPR3 (0.53) SMPD1ITPR3ITPR2ITPR1INPP5A
SCHEMBL16869500 0.82 SMPD1 (0.38) SMPD1ITPR3ITPR2ITPR1INPP5A
SCHEMBL16869663 0.80 ITPR3 (0.38) SMPD1ITPR3ITPR2ITPR1INPP5A
SCHEMBL15335159 0.75
SCHEMBL12858494 0.75
SCHEMBL16869598 0.75
SCHEMBL9295329 0.71 CA2 (0.35)
SCHEMBL12858416 0.71 CA2 (0.35)
SCHEMBL9767712 0.71 CA2 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160168607-A1 Inositol Biotransformation UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) 2016-06-16 US disclosed