Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.71 |
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
| ▸ | TLR2 | O60603 | 1/20 | 0.52 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.49 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.49 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TERT | O14746 | 2/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | GSR | P00390 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3907033 | 1.00 | MMP2 (0.71) | MMP2LTA4HTLR2GNAI3GNAO1 | |
| SCHEMBL8526418 | 0.95 | MMP2 (0.64) | MMP2LTA4HCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9275540 | 0.95 | MMP2 (0.64) | MMP2LTA4HCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3583374 | 0.89 | MMP2 (0.56) | MMP2CYP1A2CYP2D6CYP2C9TSHR | |
| SCHEMBL30120748 | 0.89 | MMP2 (0.56) | MMP2CYP1A2CYP2D6CYP2C9TSHR | |
| SCHEMBL16150370 | 0.88 | MMP2 (0.56) | MMP2SPHK1MMP8EGFRSRC | |
| SCHEMBL16150371 | 0.88 | MMP2 (0.56) | MMP2SPHK1MMP8EGFRSRC | |
| Hydrochloric Acid SCHEMBL28736783 | 0.88 | MMP2 (0.55) | MMP2CYP1A2CYP2D6CYP2C9TSHR | |
| SCHEMBL17531100 | 0.87 | SPHK1 (0.64) | MMP2TLR2GNAI3GNAO1GNAI1 | |
| SCHEMBL30889119 | 0.85 | MMP2 (0.67) | MMP2LTA4HTLR2GNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5759827-A | Acylated oligopeptides for transfecting cells | HOFFMANN-LA ROCHE INC. (US) | 1998-06-02 | — | — | US | disclosed |